User profiles for Kıvılcım Kılıç

Kıvılcım KILIÇ

Boston University, Biomedical Engineering
Verified email at bu.edu
Cited by 1927

Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection

…, S Yilmaz-Ozcan, M Yemisci, J Schallek, K Kılıç… - elife, 2018 - elifesciences.org
10.7554/eLife.34861.001 Recent evidence suggests that capillary pericytes are contractile
and play a crucial role in the regulation of microcirculation. However, failure to detect …

Cell type specificity of neurovascular coupling in cerebral cortex

H Uhlirova, K Kılıç, P Tian, M Thunemann… - elife, 2016 - elifesciences.org
10.7554/eLife.14315.001 Identification of the cellular players and molecular messengers
that communicate neuronal activity to the vasculature driving cerebral hemodynamics is …

[HTML][HTML] Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays

M Thunemann, Y Lu, X Liu, K Kılıç, M Desjardins… - Nature …, 2018 - nature.com
Recent advances in optical technologies such as multi-photon microscopy and optogenetics
have revolutionized our ability to record and manipulate neuronal activity. Combining …

Dynamic light scattering imaging

DD Postnov, J Tang, SE Erdener, K Kılıç, DA Boas - Science advances, 2020 - science.org
We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement
of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal …

High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations

TD Weber, MV Moya, K Kılıç, J Mertz… - Nature …, 2023 - nature.com
Genetically encoded voltage indicators (GEVIs) hold immense potential for monitoring neuronal
population activity. To date, best-in-class GEVIs rely on one-photon excitation. However, …

Dynamic capillary stalls in reperfused ischemic penumbra contribute to injury: a hyperacute role for neutrophils in persistent traffic jams

ŞE Erdener, J Tang, K Kılıç, D Postnov… - Journal of Cerebral …, 2021 - journals.sagepub.com
Ever since the introduction of thrombolysis and the subsequent expansion of endovascular
treatments for acute ischemic stroke, it remains to be identified why the actual outcomes are …

Simultaneous multiplane imaging with reverberation two-photon microscopy

DR Beaulieu, IG Davison, K Kılıç, TG Bifano, J Mertz - Nature methods, 2020 - nature.com
Multiphoton microscopy has gained enormous popularity because of its unique capacity to
provide high-resolution images from deep within scattering tissue. Here, we demonstrate …

Awake mouse imaging: from two-photon microscopy to blood oxygen level–dependent functional magnetic resonance imaging

M Desjardins, K Kılıç, M Thunemann, C Mateo… - Biological Psychiatry …, 2019 - Elsevier
Background Functional magnetic resonance imaging (fMRI) in awake behaving mice is well
positioned to bridge the detailed cellular-level view of brain activity, which has become …

More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction

B Li, TV Esipova, I Sencan, K Kılıç, B Fu, M Desjardins… - Elife, 2019 - elifesciences.org
10.7554/eLife.42299.001 Our understanding of how capillary blood flow and oxygen distribute
across cortical layers to meet the local metabolic demand is incomplete. We addressed …

Spatio-temporal dynamics of cerebral capillary segments with stalling red blood cells

ŞE Erdener, J Tang, A Sajjadi, K Kılıç… - Journal of Cerebral …, 2019 - journals.sagepub.com
Optical coherence tomography (OCT) allows label-free imaging of red blood cell (RBC) flux
within capillaries with high spatio-temporal resolution. In this study, we utilized time-series …