The COVID-19 pandemic has resulted in the widespread implementation of extraordinary
physical distancing interventions (eg, stay-at-home orders) to slow the spread of the virus. …

The RNA helicase eIF4A plays a key role in unwinding of mRNA and scanning during translation
initiation. Free eIF4A is a poor helicase and requires the accessory proteins eIF4G and …

Objective The social and economic consequences of COVID‐19 and related public health
interventions aimed at slowing the spread of the virus have been proposed to increase suicide …

Programmed Cell Death 4 (PDCD4) is a protein known to bind eukaryotic initiation factor 4A
(eIF4A), inhibit translation initiation, and act as a tumor suppressor. PDCD4 contains two C-…

The COVID-19 pandemic is likely to increase risk for the development of health anxiety.
Given that elevated health anxiety can contribute to maladaptive health behaviors, there is a …

Zinc (Zn) is an essential micronutrient and cofactor for up to 10% of proteins in living organisms.
During Zn limitation, specialized enzymes called metallochaperones are predicted to …

Bacterial transition metal homoeostasis or simply ‘metallostasis’ describes the process by
which cells control the intracellular availability of functionally required metal cofactors, from …

To obtain a comprehensive assessment of metabolite levels from extracts of leukocytes, we
have recorded ultrahigh-resolution 1 H− 13 C HSQC NMR spectra of cell extracts, which …

Allosteric communication between two ligand-binding sites in a protein is a central aspect of
biological regulation that remains mechanistically unclear. Here we show that perturbations …

Staphylococcus aureus is a commensal human pathogen and a major cause of nosocomial
infections. As gaseous signaling molecules, endogenous hydrogen sulfide (H 2 S) and nitric …