Multiple common variants for celiac disease influencing immune gene expression

PCA Dubois, G Trynka, L Franke, KA Hunt… - Nature …, 2010 - nature.com
We performed a second-generation genome-wide association study of 4,533 individuals with
celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with …

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

G Trynka, KA Hunt, NA Bockett, J Romanos, V Mistry… - Nature …, 2011 - nature.com
Using variants from the 1000 Genomes Project pilot European CEU dataset and data from
additional resequencing studies, we densely genotyped 183 non-HLA risk loci previously …

[HTML][HTML] Shared and distinct genetic variants in type 1 diabetes and celiac disease

…, PC Dubois, DG Clayton, KA Hunt… - … England Journal of …, 2008 - Mass Medical Soc
Background Two inflammatory disorders, type 1 diabetes and celiac disease, cosegregate in
populations, suggesting a common genetic origin. Since both diseases are associated with …

Newly identified genetic risk variants for celiac disease related to the immune response

KA Hunt, A Zhernakova, G Turner, GAR Heap… - Nature …, 2008 - nature.com
Our genome-wide association study of celiac disease previously identified risk variants in
the IL2–IL21 region. To identify additional risk variants, we genotyped 1,020 of the most …

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

DA Van Heel, L Franke, KA Hunt, R Gwilliam… - Nature …, 2007 - nature.com
We tested 310,605 SNPs for association in 778 individuals with celiac disease and 1,422
controls. Outside the HLA region, the most significant finding (rs13119723; P = 2.0 × 10 −7 ) …

A conceptual approach to classifying sports fans

KA Hunt, T Bristol, RE Bashaw - Journal of services marketing, 1999 - emerald.com
… If that end node contains positive affect and feelings, the probability increases that the child
will be motivated to engage in behavior relevant to the target sport (Hunt, 1995; Hunt and …

The power of genetic diversity in genome-wide association studies of lipids

…, K Ekoru, A Verma, B Trivedi, HC Martin, KA Hunt… - Nature, 2021 - nature.com
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use 1 . Despite …

Characteristics of frequent users of emergency departments

KA Hunt, EJ Weber, JA Showstack, DC Colby… - Annals of emergency …, 2006 - Elsevier
STUDY OBJECTIVE: We identify frequent users of the emergency department (ED) and
determine the characteristics of these patients. METHODS: Using the 2000 to 2001 population-…

[PDF][PDF] Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

…, G Gonzalez-Arroyo, CJ Griffiths, Y Guo, KA Hunt… - Cell Genomics, 2022 - cell.com
Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic
loci across a range of human diseases and traits. However, most biobanks are primarily …

Conceptualization and operationalization of retail store image: A case of rival middle-level theories

SM Keaveney, KA Hunt - Journal of the Academy of …, 1992 - journals.sagepub.com
This article presents the case that inconsistencies between retail store image conceptualization
and operationalization signal a critical separation between theory and measurement …