Very little is currently known about the major histocompatibility complex (MHC) region of
cynomolgus macaques (Macaca fascicularis; Mafa) from Chinese breeding centers. We …

Acute myeloid leukemia (AML) affects tens of thousands of patients a year, yet survival rates
are as low as 25% in certain populations. This poor survival rate is partially due to the vast …

… Katelyn Heimbruch… Cary Stelloh performed the correlative experiments and Katelyn
Heimbruch analyzed the correlative data. Michael J. Burke designed the study; Michael J. …

Acute myeloid leukemia (AML) is a high-risk malignancy characterized by a diverse spectrum
of somatic genetic alterations. The mechanisms by which these mutations contribute to …

Pig-tailed macaques (Macaca nemestrina) serve as important models for human infectious
disease research. Major histocompatibility complex (MHC) class II molecules are important to …

Acute myeloid leukemia (AML) is driven by mutations that occur in numerous combinations.
A better understanding of how mutations interact with one another to cause disease is critical …

Nonhuman primates (NHPs) are a historically important source of zoonotic viruses and are a
gold-standard model for research on many human pathogens. However, with the exception …

Gene expression is regulated by numerous elements including enhancers, insulators,
transcription factors, and architectural proteins. Regions of DNA distal to the transcriptional start …

Sooty mangabeys (Cercocebus atys) are natural SIV hosts and the presumed source of HIV-2
and SIVmac, which makes them a valuable model for HIV/SIV research. However, like …

Baboons are valuable models for complex human diseases due to their genetic and
physiologic similarities to humans. Deep sequencing methods to characterize full-length major …