Understanding how the immune system decides between tolerance and activation by antigens
requires addressing cytokine regulation as a highly dynamic process. We quantified the …

Glucocorticoid and other adipogenic hormones are secreted in mammals in circadian
oscillations. Loss of this circadian oscillation pattern correlates with obesity in humans, raising the …

… Through a combination of experimental and computational analyses, Tkach et al.
identified two novel IL-2 feedback loops that help to generate the correct quantity of cytokine, …

A hierarchical tree of the levels of choosing the optimal information and communication means
for promoting energy-saving technologies based on the hierarchy analysis method was …

The NKG2D activating receptor has been implicated in numerous autoimmune diseases.
We tested the role of NKG2D in models of autoimmunity and inflammation using NKG2D …

Genetics tools are used in applied conservation management for taxonomic identification,
delineation of management units, management of wild populations, captive breeding and …

Twenty-six patients with late infected total knee arthroplasties were treated by debridement
and removal of components and all cement, preserving collateral ligaments. At time of …

PURPOSE: Previous studies have reported decreased continence in patients undergoing
transanal endorectal pull-through (TERP) for Hirschsprung's disease compared to the older …

T cells discriminate between peptide-MHC complexes on the surfaces of antigen presenting
cells to enact appropriate downstream responses. Great progress has been made over the …

Fifty-three primary and 47 revision posterior cruciate ligament (PCL)-substituting total knee
arthroplasties (TKAs) using a highly conforming (ultracongruent) polyethylene insert were …