Pantothenic acid, a precursor of coenzyme A (CoA), is essential for the growth of pathogenic
microorganisms. Since the structure of pantothenic acid was determined, many analogues …

Throughout the latter half of this century, the development and spread of resistance to most
front-line antimalarial compounds used in the prevention and treatment of the most severe …

The altered permeability characteristics of erythrocytes infected with malaria parasites have
been a source of interest for over 30 years. Recent electrophysiological studies have …

Cell extracts from photoautrophic cultures of two cyanobacterial Calothrix isolates inhibited
the growth in vitro of a chloroquine-resistant strain of the malaria parasite, Plasmodium …

The growth of the human malaria parasite,Plasmodium falciparum, within its host erythrocyte
is reliant on the uptake of a number of essential nutrients from the extracellular medium. …

Background Flavonoids are abundant plant phenolic compounds. More than 6000 have
been identified to date, and some have been shown to possess antiparasitic activity. Here we …

The proliferation of the intraerythrocytic malaria parasite is dependent on the uptake from
the blood plasma, and from the cytoplasm of the host cell, of a range of essential nutrients. …

The mechanism by which the intra-erythrocytic form of the human malaria parasite,
Plasmodium falciparum, extrudes H + ions and thereby regulates its cytosolic pH (pH i ), was …

Chloroquine resistance in the human malaria parasite, Plasmodium falciparum, arises from
decreased accumulation of the drug in the `digestive vacuole' of the parasite, an acidic …

As it grows within the human erythrocyte, the malaria parasite, Plasmodium falciparum,
ingests the erythrocyte cytosol, depositing it via an endocytotic feeding mechanism in the "…