Recent advances in single-cell RNA sequencing technologies enable deep insights into
cellular development, gene regulation, and phenotypic diversity by measuring gene expression …

Single-cell RNA sequencing technologies suffer from many sources of technical noise,
including under-sampling of mRNA molecules, often termed "dropout," which can severely …

The high-dimensional data created by high-throughput technologies require visualization
tools that reveal data structure and patterns in an intuitive form. We present PHATE, a …

… Moon explores the contributions of writers, performers, producers, and consumers in order …
Moon shows how these performers carefully navigated between racist attitudes and their own …

It is currently challenging to analyze single-cell data consisting of many cells and samples,
and to address variations arising from batch effects and different sample preparations. For …

Single-cell RNA-sequencing is fast becoming a major technology that is revolutionizing
biological discovery in fields such as development, immunology and cancer. The ability to …

Acral melanoma occurring on the palms, soles, and nails is the most common subtype of
cutaneous melanoma in Asians. Genetic alterations in acral melanoma and acral melanocytic …

Neuropil is a fundamental form of tissue organization within the brain 1 , in which densely
packed neurons synaptically interconnect into precise circuit architecture 2 , 3 . However, the …

f-divergence estimation is an important problem in the fields of information theory, machine
learning, and statistics. While several divergence estimators exist, relatively few of their …

… Wolf, and KR Moon, “Visualizing high dimensional dynamical processes,” in MLSP, 2019.
[… Moon, “Extendable and invertible manifold learning with geometry regularized autoencoders,” …