Invasion-inhibitory antibodies elicited by immunization with Plasmodium vivax apical membrane antigen-1 expressed in Pichia pastoris yeast
EC Vicentin, KS Françoso, MV Rocha… - Infection and …, 2014 - Am Soc Microbiol
In a recent vaccine trial performed with African children, immunization with a recombinant
protein based on Plasmodium falciparum apical membrane antigen 1 (AMA-1) conferred a …
protein based on Plasmodium falciparum apical membrane antigen 1 (AMA-1) conferred a …
[HTML][HTML] A recombinant vaccine based on domain II of Plasmodium vivax Apical Membrane Antigen 1 induces high antibody titres in mice
F Gentil, DY Bargieri, JA Leite, KS Françoso… - Vaccine, 2010 - Elsevier
The Apical Membrane Antigen 1 (AMA-1) is considered a promising candidate for development
of a malaria vaccine against asexual stages of Plasmodium. We recently identified …
of a malaria vaccine against asexual stages of Plasmodium. We recently identified …
[HTML][HTML] Prime-boost vaccination with recombinant protein and adenovirus-vector expressing Plasmodium vivax circumsporozoite protein (CSP) partially protects …
…, LC Lima, K de Almeida Caramico, KS Françoso… - Scientific reports, 2018 - nature.com
Vaccine development against Plasmodium vivax malaria lags behind that for Plasmodium
falciparum. To narrow this gap, we administered recombinant antigens based on P. vivax …
falciparum. To narrow this gap, we administered recombinant antigens based on P. vivax …
[HTML][HTML] Therapeutic treatment with scFv–PLGA nanoparticles decreases pulmonary fungal load in a murine model of paracoccidioidomycosis
GP Jannuzzi, N de Araújo Souza, KS Françoso… - Microbes and …, 2018 - Elsevier
Paracoccidioidomycosis (PCM) is a systemic mycosis with lymphatic dissemination that is
caused by Paracoccidioides species. Treatment of PCM consists of chemotherapeutics such …
caused by Paracoccidioides species. Treatment of PCM consists of chemotherapeutics such …
[HTML][HTML] Vaccine Containing the Three Allelic Variants of the Plasmodium vivax Circumsporozoite Antigen Induces Protection in Mice after Challenge with a …
AM Gimenez, LC Lima, KS Francoso… - Frontiers in …, 2017 - frontiersin.org
Plasmodium vivax is the most common species that cause malaria outside of the African
continent. The development of an efficacious vaccine would contribute greatly to control malaria…
continent. The development of an efficacious vaccine would contribute greatly to control malaria…
[HTML][HTML] A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2a1, MSA-2b and MSA-2c elicits invasion …
AM Gimenez, KS Françoso, J Ersching, MY Icimoto… - Parasites & vectors, 2016 - Springer
Background Babesia bovis is a tick-transmitted protozoan hemoparasite and the causative
agent of bovine babesiosis, a potential risk to more than 500 million cattle worldwide. The …
agent of bovine babesiosis, a potential risk to more than 500 million cattle worldwide. The …
Generation, characterization and immunogenicity of a novel chimeric recombinant protein based on Plasmodium vivax AMA-1 and MSP119
MV Rocha, KS Françoso, LC Lima, TM Camargo… - Vaccine, 2017 - Elsevier
Plasmodium vivax is the most widely distributed malaria species and the most prevalent
species of malaria in America and Asia. Vaccine development against P. vivax is considered a …
species of malaria in America and Asia. Vaccine development against P. vivax is considered a …
[HTML][HTML] Febrile temperatures increase in vitro antibody affinity for malarial and dengue antigens
Fever is a regulated increase of the body temperature resulting from both infectious and non-infectious
causes. Fever is known to play a role in modulating immune responses to …
causes. Fever is known to play a role in modulating immune responses to …
Poly I:C elicits broader and stronger humoral and cellular responses to a Plasmodium vivax circumsporozoite protein malaria vaccine than Alhydrogel in mice
TBL Costa-Gouvea, KS Françoso, RF Marques… - Frontiers in …, 2024 - frontiersin.org
Malaria remains a global health challenge, necessitating the development of effective
vaccines. The RTS,S vaccination prevents Plasmodium falciparum (Pf) malaria but is ineffective …
vaccines. The RTS,S vaccination prevents Plasmodium falciparum (Pf) malaria but is ineffective …
[HTML][HTML] A Multistage Formulation Based on Full-Length CSP and AMA-1 Ectodomain of Plasmodium vivax Induces High Antibody Titers and T-cells and Partially Protects Mice …
LC Lima, RF Marques, AM Gimenez, KS Françoso… - Microorganisms, 2020 - mdpi.com
Infections with Plasmodium vivax are predominant in the Americas, representing 75% of
malaria cases. Previously perceived as benign, malaria vivax is, in fact, a highly debilitating and …
malaria cases. Previously perceived as benign, malaria vivax is, in fact, a highly debilitating and …