Deep entorhinal cortex: from circuit organization to spatial cognition and memory

KZ Gerlei, CM Brown, G Sürmeli, MF Nolan - Trends in Neurosciences, 2021 - cell.com
The deep layers of the entorhinal cortex are important for spatial cognition, as well as
memory storage, consolidation and retrieval. A long-standing hypothesis is that deep-layer …

[PDF][PDF] Stellate cells in the medial entorhinal cortex are required for spatial learning

SA Tennant, L Fischer, DLF Garden, KZ Gerlei… - Cell Reports, 2018 - cell.com
Spatial learning requires estimates of location that may be obtained by path integration or
from positional cues. Grid and other spatial firing patterns of neurons in the superficial medial …

Big data reduction by fitting mathematical functions: A search for appropriate functions to fit Ramachandran surfaces

A Rágyanszki, KZ Gerlei, A Surányi, A Kelemen… - Chemical Physics …, 2015 - Elsevier
The potential energy surface associated with internal rotation of a pair of geminal functional
groups was studied using electron structure calculations. The functional groups were …

[PDF][PDF] Spatial representation by ramping activity of neurons in the retrohippocampal cortex

…, H Clark, I Hawes, WK Tam, J Hua, W Yang, KZ Gerlei… - Current Biology, 2022 - cell.com
Neurons in the retrohippocampal cortices play crucial roles in spatial memory. Many
retrohippocampal neurons have firing fields that are selectively active at specific locations, with …

Reactivity of Ala-Gly dipeptide with β-turn secondary structure

PY Craig, KZ Gerlei, A Rágyanszki, SJK Jensen… - Chemical Physics …, 2018 - Elsevier
The conformational space of β-turns of Ala-Gly dipeptide is analyzed theoretically using
quantum mechanical methods. A number of potential minima are obtained and characterized. …

Bayesian inference of grid cell firing patterns using Poisson point process models with latent oscillatory Gaussian random fields

…, G Auld, F Lindgren, KZ Gerlei… - arXiv preprint arXiv …, 2023 - arxiv.org
Questions about information encoded by the brain demand statistical frameworks for inferring
relationships between neural firing and features of the world. The landmark discovery of …

Atropisomerism of the Asn α radicals revealed by Ramachandran surface topology

KZ Gerlei, I Jákli, M Szőri, SJK Jensen… - The Journal of …, 2013 - ACS Publications
C radicals are typically trigonal planar and thus achiral, regardless of whether they originate
from a chiral or an achiral C-atom (eg, C–H + • OH → C• + H 2 O). Oxidative stress could …

Impairment of a model peptide by oxidative stress: Thermodynamic stabilities of asparagine diamide Cα-radical foldamers

KZ Gerlei, L Élő, B Fiser, MC Owen, I Jákli… - Chemical Physics …, 2014 - Elsevier
Electron structure calculations on N-acetyl asparagine N-methylamide were performed to
identify the global minimum from which radicals were formed after H-abstraction by the OH …

A comparison of l-and d-Asp and Asn α-radicals a case study for atropisomerism

KZ Gerlei, SY Uysal - Computational and Theoretical Chemistry, 2014 - Elsevier
Asp radical has enantiomeric d and l form, due to axis chirality. This pair of degenerate minima
is occurring on a single 4D-Ramachandran Potential Energy Hyper Surface (PEHS). The …

Anatomical and functional investigation of the deep medial entorhinal cortex

KZ Gerlei - 2019 - era.ed.ac.uk
Spatial computations are thought to be processed in the hippocampal-entorhinal network
and involve neurons with spatially selective firing properties. The deep medial entorhinal …