… Karen Burns drafted a template of the guide, reviewed and synthesized pertinent literature
and prepared the initial and subsequent drafts of the manuscript. Mark Duffett and Michelle …

The production of functional female gametes is essential for the propagation of all vertebrate
species. The growth of oocytes within ovarian follicles and their development to mature …

Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …

… Despite its relatively low incidence, carbapenem-resistant K pneumoniae had a high
burden of disease because of its high attributable mortality, whereas vancomycin-resistant E …

The widely expressed protein Fas is a member of the tumour necrosis factor receptor family
which can trigger apoptosis 1 . However, Fas surface expression does not necessarily …

Generation of Interleukin (IL)-1β via cleavage of its proform requires the activity of caspase-1
(and caspase-11 in mice), but the mechanism involved in the activation of the …

Viruses have evolved many distinct strategies to avoid the host's apoptotic response 1,2 .
Here we describe a new family of viral inhibitors (v-FLIPs) which interfere with apoptosis …

Mutations within the NALP3/cryopyrin/CIAS1 gene are responsible for three autoinflammatory
disorders: Muckle-Wells syndrome, familial cold autoinflammatory syndrome, and CINCA. …

Stimulation of Toll-like receptors (TLRs) initiates potent innate immune responses through
Toll–interleukin 1 receptor (TIR) domain–containing adaptors such as MyD88 and Trif. …

With the increasing use of cocaine in the United States, there has been growing concern
regarding its effects on the fetuses and neonates of pregnant cocaine abusers. Twenty-three …