Postnatal brain development is studded with sensitive periods during which experience
dependent plasticity is enhanced. This enables rapid learning from environmental inputs and …

Across species, adolescence is a period of growing independence that is associated with
the maturation of cognitive, social, and affective processing. Reorganization of neural circuits …

Although the medial prefrontal cortex (mPFC) is classically defined by its reciprocal connections
with the mediodorsal thalamic nucleus (MD), the nature of information transfer between …

Odors elicit distributed activation of glomeruli in the olfactory bulb (OB). Crosstalk between
co-active glomeruli has been proposed to perform a variety of computations, facilitating …

Neuromodulation plays a critical role in brain function in both health and disease, and new
tools that capture neuromodulation with high spatial and temporal resolution are needed. …

… A k-means (k = 2) cluster analysis was applied to a database consisting of 574 mice subjected
to the LH procedure (Fig. 1). We used failures and escape latency—the most commonly …

Degeneration of the dopaminergic nigrostriatal system and of noradrenergic neurons in the
locus coeruleus are important pathological features of Parkinson’s disease. There is an …

Neuregulin-1 (NRG1) and its receptor ErbB4 influence several processes of neurodevelopment,
but the mechanisms regulating this signalling in the mature brain are not well known. …

Individuals with schizophrenia demonstrate impairments of sensory processing within primary
auditory cortex. We have previously identified lower densities of dendritic spines and axon …

Highlights • Dopamine neurons and their striatal and cortical circuit targets support learning
and decision making. • These circuits and behaviors show protracted development into …