Background In March 2003, several hospitals in Quebec, Canada, noted a marked increase
in the incidence of Clostridium difficile–associated diarrhea. Methods In 2004 we conducted …

Linkage disequilibrium (LD) mapping provides a powerful method for fine-structure localization
of rare disease genes, but has not yet been widely applied to common disease 1. We …

Nonhuman primates (NHP) provide crucial biomedical model systems intermediate between
rodents and humans. The vervet monkey (also called the African green monkey) is a widely …

… 32) and assembled with the Ray assembler 78 using a K-mer size of 31 to 41 (optimized per
… then scaffolded using SOAPdenovo 79 with a K-mer size of 61 and with gap filling enabled. …

The genome of the flowering plant Arabidopsis thaliana has five chromosomes 1 , 2 . Here
we report the sequence of the largest, chromosome 1, in two contigs of around 14.2 and 14.6 …

… by treating the protein/DNA complex with Proteinase K. Finally, the DNA was purified with …
Fisher’s combined p value calculated for k number of p values by c2 ¼ À2Ploge(p valuek) …

Insulin from the β-cells of the pancreatic islets of Langerhans controls energy homeostasis
in vertebrates, and its deficiency causes diabetes mellitus. During embryonic development, …

OBJECTIVE: Postmortem studies have indicated that suicide victims have greater serotonin
receptor 2A (5-HTR 2A ) binding in prefrontal brain regions. However, there remains some …

… Zody, Jennifer Baldwin, Keri Devon, Ken Dewar, Michael Doyle, William Fitzhugh, Roel
Funke, Diane Gage, Katrina Harris, Andrew Heaford, John Howland, Lisa Kann, Jessica …

Cis-acting variants altering gene expression are a source of phenotypic differences. The cis-acting
components of expression variation can be identified through the mapping of …