SRY, the mammalian Y-chromosomal testis-determining gene, induces male sex
determination. Recent studies in mice reveal that the major role of SRY is to achieve sufficient …

This International Consensus Guideline was developed by experts in the field of small for
gestational age (SGA) of 10 pediatric endocrine societies worldwide. A consensus meeting …

Follistatin is a secreted glycoprotein required for female sex determination and early ovarian
development, but the precise mechanisms regulating follistatin (Fst) gene expression are …

Purpose Autoantibodies (aAbs) to type I interferons (IFNs) have been found in less than 1%
of individuals under the age of 60 in the general population, with the prevalence increasing …

Sex determination in fetal germ cells depends on a balance between exposure to retinoic acid
(RA) and the degradation of RA achieved by the testis-specific expression of the catabolic …

… Figure 8 suggests that the observed valuesof k would be explained by I in the case of the
experiment with a fluorescent lamp as well as with sunlight. Figure 9 suggests that the …

… Proteinase K was added to the reaction mixtures and incubated at 37C for 1 h. DNA from
the immunoprecipitates and control input DNA were purified and then analyzed by qRT-PCR. …

… The collected information included the diagnosis of the patients including the type of CAH,
laboratory data before the start of the treatment (17-OHP, Na, K), and the brief clinical course …

The role of monogenic mutations in the development of 46,XX testicular/ovotesticular disorders
of sex development (DSD) remains speculative. Although mutations in NR5A1 are known …

… classical 21OHD patients, the serum Na and K levels linearly deteriorated with age in days,
and the age when the regression lines reached Na < 130 mEq/L, K > 7 mEq/L approximately …