The neural circuits responsible for animal behavior remain largely unknown. We summarize
new methods and present the circuitry of a large fraction of the brain of the fruit fly …

… (H–K) Serial thin sections succeeding the one in (F). Fine processes can be followed across
serial sections and section-to-section image registration is accurate enough to provide a …

Recording light-microscopy images of large, nontransparent specimens, such as developing
multicellular organisms, is complicated by decreased contrast resulting from light scattering. …

… where K is the number of objects in the image, μ k is the center location of each nucleus, Σ
k is the covariance matrix (representing the shape of each nucleus as an ellipsoid) and π k is …

Novel approaches to bio‐imaging and automated computational image processing allow
the design of truly quantitative studies in developmental biology. Cell behavior, cell fate …

The neural circuits responsible for behavior remain largely unknown. Previous efforts have
reconstructed the complete circuits of small animals, with hundreds of neurons, and selected …

Light sheet-based fluorescence microscopy (LSFM) is emerging as a powerful imaging
technique for the life sciences. LSFM provides an exceptionally high imaging speed, high signal-…

We show that homotypic and heterotypic mechanisms of LLPS control NUP98–HOXA9
puncta formation, modulating transcriptional activity and transforming hematopoietic cells. …

… where A k x ⁠, B k x ⁠, A k y ⁠, and B k y are the expansion coefficients. The lower indices k
apply to the k … The k = 0 component corresponds to the center of mass of the perimeter. The …

Collagen fibres within the extracellular matrix lend tensile strength to tissues and form a
functional scaffold for cells. Cells can move directionally along the axis of fibrous structures, in a …