User profiles for K. Kunji

Khalid Kunji

Hamad Bin Khalifa University, Qatar Computing Research Institute
Verified email at hbku.edu.qa
Cited by 770

DeepSol: a deep learning framework for sequence-based protein solubility prediction

S Khurana, R Rawi, K Kunji, GY Chuang… - …, 2018 - academic.oup.com
… ( f k , q k , a k ) } k = 1 to K ⁠, where f k is the convolution filter size, q k is the number of
convolutional filters and a k is … ( f k , q k , a k ) (see Section 2 for explanation of notation). We drop a …

PaRSnIP: sequence-based protein solubility prediction using gradient boosting machine

R Rawi, R Mall, K Kunji, CH Shen, PD Kwong… - …, 2018 - academic.oup.com
Motivation Protein solubility can be a decisive factor in both research and production efficiency,
and in silico sequence-based predictors that can accurately estimate solubility outcomes …

DeepCrystal: a deep learning framework for sequence-based protein crystallization prediction

A Elbasir, B Moovarkumudalvan, K Kunji… - …, 2019 - academic.oup.com
… The feature representations learnt by our model, such as k-mer information and frequent sets
of amino acid k-mers help in identifying discriminative features for predicting which proteins …

RGBM: regularized gradient boosting machines for identification of the transcriptional regulators of discrete glioma subtypes

…, L Cerulo, L Garofano, V Frattini, K Kunji… - Nucleic acids …, 2018 - academic.oup.com
… where k represents a node in the regression tree, |$w^{t}_{jk}$|⁠, |$w^{t}_{jkl}$| and |$w^{t}_{jkr}$|
correspond to number of samples in node k, the left branch of k and right branch of k

Genetic predisposition to cancer across people of different ancestries in Qatar: a population-based, cohort study

…, Y Mokrab, N Halabi, J Shan, R Razali, K Kunji… - The Lancet …, 2022 - thelancet.com
Background Disparities in the genetic risk of cancer among various ancestry groups and
populations remain poorly defined. This challenge is even more acute for Middle Eastern …

BCrystal: an interpretable sequence-based protein crystallization predictor

A Elbasir, R Mall, K Kunji, R Rawi, Z Islam… - …, 2020 - academic.oup.com
… These features can be associated with the frequencies of k-mers and sets of k-mers of
different lengths. However, it is not straightforward to pinpoint what are the specific k-mers in a …

Network-based identification of key master regulators associated with an immune-silent cancer phenotype

…, M Saad, J Roelands, D Rinchai, K Kunji… - Briefings in …, 2021 - academic.oup.com
… Khalid Kunji is a software engineer at QCRI with a background in biophysics and mathematics.
His work includes protein property prediction, family-based imputation and other work in …

Open community challenge reveals molecular network modules with key roles in diseases

…, D Korkin, K Krzysztof, K Kunji, Z Kutalik, K Lage… - bioRxiv, 2018 - biorxiv.org
… modules recovered by the top K methods. Given the top K methods, we considered the set
… From the set of trait-associated modules discovered by the top K methods, we thus derived …

Validation of polygenic risk scores for Coronary Heart Disease in a Middle Eastern Cohort using whole genome sequencing

M Saad, A El-Menyar, K Kunji, E Ullah… - Circulation: Genomic …, 2022 - Am Heart Assoc
… The authors also thank Yusef Kunji for valuable discussions and comments on biochemical
pathways and gene function and Fayaz Mir for the help with sample acquisition in QCBio. …

Comparison and assessment of family-and population-based genotype imputation methods in large pedigrees

E Ullah, R Mall, MM Abbas, K Kunji, AQ Nato… - Genome …, 2019 - genome.cshlp.org
Genotype imputation is widely used in genome-wide association studies to boost variant
density, allowing increased power in association testing. Many studies currently include …