Zika virus (ZIKV) is a flavivirus that has recently been associated with an increased
incidence of neonatal microcephaly and other neurological disorders. The virus is primarily …

The phosphodiesterase type 5 (PDE5) inhibitor, Sildenafil, is a novel, oral treatment approach
for pulmonary hypertension. As Leydig cells present PDE5, this study was conducted to …

Microemulsion containing pentoxifylline was developed and characterized for use as a
topical alternative to treat skin disorders. The transparent formulation was developed and …

The objective of the present study was to evaluate, by light and transmission electron
microscopy, the efficacy of a single intratesticular injection of a novel zinc-based solution, as a …

Chikungunya virus (CHIKV) is an arthropod-borne virus recently associated with large
outbreaks in many parts of the world. Infection is typically manifested as a febrile and self-limited …

β-Caryophyllene (β-CP) is a bioactive sesquiterpene abundant in copaiba oil-resin (COR),
which is widely used in Brazilian folk medicine; however, its instability due to the presence of …

… Ximenes, Giovanna Machado, and Karina LA Saraiva wrote the manuscript. All authors …
Ximenes, Giovanna Machado, and Karina LA Saraiva also contributed equally to this work. …

Gold nanorods (AuNRs) have been studied extensively in biomedicine due to their
biocompatibility and their unique properties. Some studies reported that AuNRs selectively …

Diethylcarbamazine (DEC) had been proved to be highly effective against lymphatic filariasis,
however its effect on vertebrate cells remains uncertain. After 12 days treatment with DEC, …

This study assessed the efficacy of ozone (bubble diffusion in water; 6.25 ppm) and photodynamic
inactivation (PDT) using curcumin (75 μM) as photosensitizer (LED emission 430–470 …