User profiles for K. Mahdaviani

Kaveh Mahdaviani

- Verified email at mail.utoronto.ca - Cited by 314

Kimia Mahdaviani

- Verified email at mail.utoronto.ca - Cited by 111

[PDF][PDF] Mitochondria bound to lipid droplets have unique bioenergetics, composition, and dynamics that support lipid droplet expansion

IY Benador, M Veliova, K Mahdaviani, A Petcherski… - Cell metabolism, 2018 - cell.com
… (J and K) Confocal imaging of living cultured brown adipocytes stained with membrane
potential-sensitive dye TMRE. (J) Confocal imaging before and after addition of the ATP synthase …

Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

JD Wikstrom, K Mahdaviani, M Liesa, SB Sereda… - The EMBO …, 2014 - embopress.org
Adrenergic stimulation of brown adipocytes ( BA ) induces mitochondrial uncoupling, thereby
increasing energy expenditure by shifting nutrient oxidation towards thermogenesis. Here …

[HTML][HTML] MoVi: A large multi-purpose human motion and video dataset

S Ghorbani, K Mahdaviani, A Thaler, K Kording… - Plos one, 2021 - journals.plos.org
Large high-quality datasets of human body shape and kinematics lay the foundation for
modelling and simulation approaches in computer vision, computer graphics, and biomechanics. …

Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis

K Mahdaviani, IY Benador, S Su, RA Gharakhanian… - EMBO …, 2017 - embopress.org
BAT ‐controlled thermogenic activity is thought to be required for its capacity to prevent the
development of insulin resistance. This hypothesis predicts that mediators of thermogenesis …

[PDF][PDF] Mitochondrial retrograde signaling in mammals is mediated by the transcriptional cofactor GPS2 via direct mitochondria-to-nucleus translocation

…, B Tanasa, CT Cederquist, J Huang, K Mahdaviani… - Molecular cell, 2018 - cell.com
As most of the mitochondrial proteome is encoded in the nucleus, mitochondrial functions
critically depend on nuclear gene expression and bidirectional mito-nuclear communication. …

Movi: A large multipurpose motion and video dataset

S Ghorbani, K Mahdaviani, A Thaler, K Kording… - arXiv preprint arXiv …, 2020 - arxiv.org
Human movements are both an area of intense study and the basis of many applications
such as character animation. For many applications, it is crucial to identify movements from …

ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity

…, S Su, K Chella Krishnan, K Mahdaviani… - Science translational …, 2021 - science.org
… (K) Hematoxylin and eosin staining of liver sections. Scale bars, 100 μm. (L) Liver TG …
Transgenic Core, directed by GL Martin and K. Ravid. Seven male chimeras containing floxed …

A study of {SSD} reliability in large scale enterprise storage deployments

S Maneas, K Mahdaviani, T Emami… - 18th USENIX Conference …, 2020 - usenix.org
This paper presents the first large-scale field study of NAND-based SSDs in enterprise
storage systems (in contrast to drives in distributed data center storage systems). The study is …

Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling

…, CM Ferreira, IY Benador, AE Jones, K Mahdaviani… - EMBO …, 2020 - embopress.org
Combined fatty acid esterification and lipolysis, termed lipid cycling, is an ATP‐consuming
process that contributes to energy expenditure. Therefore, interventions that stimulate energy …

Autocrine effect of vascular endothelial growth factor-A is essential for mitochondrial function in brown adipocytes

K Mahdaviani, D Chess, Y Wu, O Shirihai… - Metabolism, 2016 - Elsevier
Objective The obesity epidemic in the United States, as well as the accompanying condition
of type 2 diabetes, puts a majority of the population at an increased risk of developing …