User profiles for K. Numata

Keiji Numata

Kyoto University
Verified email at kyoto-u.ac.jp
Cited by 10036

[HTML][HTML] Biopolymer-based nanoparticles for drug/gene delivery and tissue engineering

SK Nitta, K Numata - International journal of molecular sciences, 2013 - mdpi.com
There has been a great interest in application of nanoparticles as biomaterials for delivery
of therapeutic molecules such as drugs and genes, and for tissue engineering. In particular, …

The biomedical use of silk: past, present, future

C Holland, K Numata… - Advanced healthcare …, 2019 - Wiley Online Library
Humans have long appreciated silk for its lustrous appeal and remarkable physical
properties, yet as the mysteries of silk are unraveled, it becomes clear that this outstanding …

Silk-based delivery systems of bioactive molecules

K Numata, DL Kaplan - Advanced drug delivery reviews, 2010 - Elsevier
Silks are biodegradable, biocompatible, self-assembling proteins that can also be tailored via
genetic engineering to contain specific chemical features, offering utility for drug and gene …

Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial

…, J Lee, D Li, A Manhas, GA Manji, K Numata… - The Lancet …, 2018 - thelancet.com
Background Immune checkpoint blockade therapy has shown promising results in patients
with advanced hepatocellular carcinoma. We aimed to assess the efficacy and safety of …

The Japanese space gravitational wave antenna: DECIGO

…, J Yokoyama, I Funaki, K Numata, K Ioka… - … and Quantum Gravity, 2011 - iopscience.iop.org
The objectives of the DECi-hertz Interferometer Gravitational Wave Observatory (DECIGO)
are to open a new window of observation for gravitational wave astronomy and to obtain …

Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study

MS Lee, BY Ryoo, CH Hsu, K Numata, S Stein… - The Lancet …, 2020 - thelancet.com
Background Dual blockade of PD-L1 and VEGF has enhanced anticancer immunity through
multiple mechanisms and augmented antitumour activity in multiple malignancies. We …

Thermal-noise limit in the frequency stabilization of lasers with rigid cavities

K Numata, A Kemery, J Camp - Physical review letters, 2004 - APS
We evaluate thermal noise (Brownian motion) in a rigid reference cavity used for frequency
stabilization of lasers, based on the mechanical loss of cavity materials and the numerical …

The Japanese space gravitational wave antenna—DECIGO

…, M Ando, N Seto, K Tsubono, K Numata… - … and Quantum Gravity, 2006 - iopscience.iop.org
DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese
space gravitational wave antenna. It aims at detecting various kinds of gravitational waves …

Innate immune response in Th1-and Th2-dominant mouse strains

H Watanabe, K Numata, T Ito, K Takagi, A Matsukawa - Shock, 2004 - journals.lww.com
C57BL/6 and BALB/c mice are prototypical Th1-and Th2-type mouse strains, respectively. In
the present study, we attempted to characterize the innate immune response of …

Midterm outcomes in patients with intermediate‐sized hepatocellular carcinoma: a randomized controlled trial for determining the efficacy of radiofrequency ablation …

…, K Numata, M Kondou, A Nozaki, S Morita, K Tanaka - Cancer, 2010 - Wiley Online Library
… At 1 month after the procedure, we evaluated the serum levels of alpha-fetoprotein and
protein induced by vitamin K absence or antagonist II (PIVKA-II). We calculated the rate at which …