Cytokinesis, the final step in cell division, partitions the contents of a single cell into two. In
animal cells, cytokinesis occurs through cortical remodeling orchestrated by the anaphase …

… We would like to thank the members of the Oegema and Desai labs for fruitful discussions
in preparation of this manuscript. We would also like to thank the UCSD mitosis club. This …

Microtubules are intrinsically polar structures. A consequence of this polarity is that the two
ends of the microtubule polymer exhibit different properties. The more dynamic plus ends and …

A key challenge of functional genomics today is to generate well-annotated data sets that
can be interpreted across different platforms and technologies. Large-scale functional …

… k, l, About 20 min after pronuclear migration. In wild type (k), the anterior blastomere (AB) is
completing division, whereas the posterior blastomere (P 1 ), follows 2–3 min later; note that …

Centrioles are ancient organelles that build centrosomes, the major microtubule-organizing
centers of animal cells. Extra centrosomes are a common feature of cancer cells. To …

… Hyman, Karen Oegema; Aurora-A kinase is required for centrosome maturation in
Caenorhabditis elegans . J Cell Biol 24 December 2001; 155 (7): 1109–1116. doi: https://doi.org/…

… elegans condensin subunits leads to more severe mitotic segregation defects than those
resulting from depletion of the chromosomal passengers (Oegema, K., unpublished …

Kinetochores play an essential role in chromosome segregation by forming dynamic
connections with spindle microtubules. Here, we identify a set of 10 copurifying kinetochore …

γ-tubulin exists in two related complexes in Drosophila embryo extracts (Moritz, M., Y. Zheng,
BM Alberts, and K. Oegema. 1998. J. Cell Biol. 142:1– 12). Here, we report the purification …