A goal of phylogeography is to relate patterns of genetic differentiation to potential historical
geographic isolating events. Quaternary glaciations, particularly the one culminating in the …

Rapid microbiologic tests provide opportunities for antimicrobial stewardship programs to
improve antimicrobial use and clinical and economic outcomes. Standard techniques for …

Phytoestrogens are a group of plant‐derived substances that are structurally or functionally
similar to estradiol. Interest in phytoestrogens has been fueled by epidemiologic data that …

Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …

Background Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration
of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly …

Single-cell RNA sequencing (scRNA-seq) is a powerful tool for defining cellular diversity in
tumors, but its application toward dissecting mechanisms underlying immune-modulating …

Invertebrate species represent more than 99% of animal diversity; however, they receive
much less publicity and attract disproportionately minor research effort relative to vertebrates. …

As a disease-modifying approach for Alzheimer's disease (AD), clioquinol (CQ) targets β-amyloid
(Aß) reactions with synaptic Zn and Cu yet promotes metal uptake. Here we …

Alzheimer's Disease (AD) is complicated by pro-oxidant intraneuronal Fe 2+ elevation as
well as extracellular Zn 2+ accumulation within amyloid plaque. We found that the AD β-…

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2, has spread globally, and no proven treatments are available. Convalescent plasma …