Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial
…, H Tinkanen, R Bloigu, K Puukka… - The Journal of …, 2012 - academic.oup.com
Background: The role of metformin in the treatment of infertility in women with polycystic ovary
syndrome (PCOS) is still controversial. Objective and Outcomes: We investigated whether …
syndrome (PCOS) is still controversial. Objective and Outcomes: We investigated whether …
Overweight and obese but not normal weight women with PCOS are at increased risk of type 2 diabetes mellitus—a prospective, population-based cohort study
…, J Jokelainen, J Auvinen, K Puukka… - Human …, 2017 - academic.oup.com
STUDY QUESTION What are the respective roles of polycystic ovary syndrome (PCOS),
long-term weight gain and obesity for the development of prediabetes or Type 2 diabetes …
long-term weight gain and obesity for the development of prediabetes or Type 2 diabetes …
Weight gain and dyslipidemia in early adulthood associate with polycystic ovary syndrome: prospective cohort study
MME Ollila, T Piltonen, K Puukka… - The Journal of …, 2016 - academic.oup.com
Context: Obesity affects the majority of women with polycystic ovary syndrome (PCOS), but
previous studies are inconsistent about the prevalence of obesity and the importance of …
previous studies are inconsistent about the prevalence of obesity and the importance of …
[HTML][HTML] Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts
…, J Kettunen, J Jokelainen, J Auvinen, K Puukka… - Diabetologia, 2019 - Springer
Aims/hypothesis Metabolomics technologies have identified numerous blood biomarkers for
type 2 diabetes risk in case−control studies of middle-aged and older individuals. We aimed …
type 2 diabetes risk in case−control studies of middle-aged and older individuals. We aimed …
[HTML][HTML] Effect of moderate alcohol consumption on liver enzymes increases with increasing body mass index
PI Alatalo, HM Koivisto, JP Hietala, KS Puukka… - The American journal of …, 2008 - Elsevier
Background: Although both ethanol consumption and overweight alter the activities of
hepatic enzymes in circulation, the differentiation of an alcohol or nonalcohol basis for such …
hepatic enzymes in circulation, the differentiation of an alcohol or nonalcohol basis for such …
Irregular menstruation and hyperandrogenaemia in adolescence are associated with polycystic ovary syndrome and infertility in later life: Northern Finland Birth …
…, H Lashen, A Bloigu, S Franks, K Puukka… - Human …, 2014 - academic.oup.com
STUDY QUESTION Do teenage girls with a history of menstrual irregularity and/or elevated
androgen levels in adolescence exhibit an increased risk of polycystic ovary syndrome (…
androgen levels in adolescence exhibit an increased risk of polycystic ovary syndrome (…
Androgen profile through life in women with polycystic ovary syndrome: a Nordic multicenter collaboration study
…, A Ruokonen, K Puukka… - The Journal of …, 2015 - academic.oup.com
… Katri Puukka , Katri Puukka … Piltonen, Johanna Puurunen, Eszter Vanky, Inger
Sundström-Poromaa, Elisabet Stener-Victorin, Aimo Ruokonen, Katri Puukka, Juha S. Tapanainen, …
Sundström-Poromaa, Elisabet Stener-Victorin, Aimo Ruokonen, Katri Puukka, Juha S. Tapanainen, …
Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates
…, M Tiainen, T Tynkkynen, K Puukka… - International journal …, 2015 - academic.oup.com
Background: The causal role of circulating sex hormone-binding globulin (SHBG) for type 2
diabetes is controversial. Information on the relations between SHBG and new biomarkers of …
diabetes is controversial. Information on the relations between SHBG and new biomarkers of …
[HTML][HTML] Normo-and hyperandrogenic women with polycystic ovary syndrome exhibit an adverse metabolic profile through life
P Pinola, K Puukka, TT Piltonen, J Puurunen, E Vanky… - Fertility and sterility, 2017 - Elsevier
Objective To compare the metabolic profiles of normo- and hyperandrogenic women with
polycystic ovary syndrome (PCOS) with those of control women at different ages during …
polycystic ovary syndrome (PCOS) with those of control women at different ages during …
Psychological distress is more prevalent in fertile age and premenopausal women with PCOS symptoms: 15-year follow-up
…, J Auvinen, A Ruokonen, K Puukka… - The Journal of …, 2017 - academic.oup.com
… Katri Puukka , Katri Puukka … Salla Karjula, Laure Morin-Papunen, Juha Auvinen, Aimo
Ruokonen, Katri Puukka, Stephen Franks, Marjo-Riitta Järvelin, Juha S. Tapanainen, Jari …
Ruokonen, Katri Puukka, Stephen Franks, Marjo-Riitta Järvelin, Juha S. Tapanainen, Jari …