Background and aim Narcolepsy is an uncommon hypothalamic disorder of presumed
autoimmune origin that usually requires lifelong treatment. This paper aims to provide evidence‐…

Background Restless legs syndrome is a prevalent chronic neurological disorder with
potentially severe mental and physical health consequences. Clearer understanding of the …

The aim of this European initiative is to facilitate a structured discussion to improve the next
edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter …

Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson’s
disease, dementia with Lewy bodies, and multiple system atrophy. This provides an …

… Sonka… Dr Sonka was involved in two trials with Orphan and is currently involved in a
trial with Cephalon. Dr Sonka is also a member of the Xyrem advisory board. …

We identified association of restless legs syndrome (RLS) with PTPRD at 9p23–24 in 2,458
affected individuals and 4,749 controls from Germany, Austria, Czechia and Canada. Two …

Objective To assess whether risk factors for Parkinson disease and dementia with Lewy
bodies increase rate of defined neurodegenerative disease in idiopathic rapid eye movement (…

Background: Kleine-Levin syndrome (KLS) is a rare disorder of unknown etiology.
Pathophysiologic hypotheses include a hypothalamic dysfunction and abnormalities in the central …

Objectives We aimed to provide a consensus statement by the International Rapid Eye
Movement Sleep Behavior Disorder Study Group (IRBD-SG) on devising controlled active …

The neurodegenerative synucleinopathies, including Parkinson’s disease and dementia
with Lewy bodies, are characterized by a typically lengthy prodromal period of progressive …