The trillions of microorganisms (microbiota) found within the human gut play a critical role in
shaping the immune system, yet these complex microbial communities are also highly …

Emerging evidence suggests that the use of non-antibiotic drugs can alter the human gut
microbiota with unknown consequences for treatment outcomes. Here, we use a combination …

Background and Aims The gut microbiota plays an important role in the metabolization and
modulation of several types of drugs. With this study we aimed to review the literature relating …

… Mr Stapleton's grey, Bridget Mr Shuttleworth's chefnut Lord Cheſterfield's bay Lord
Lonfdale's chefnut … Mr Stapleton's grey mare, Bridget Mr Howard's white horfe, Crutches …

Methotrexate (MTX) is a chemotherapeutic agent that can cause a range of toxic side effects
including gastrointestinal damage, hepatotoxicity, myelosuppression, and nephrotoxicity …

… For instance, different strains of K. pneumoniae show variable potential in activating type
1 T helper (Th) cells, highlighting the importance of accessory genes on modulating immune …

Despite the recognition, nearly a century ago, that the human microbiome plays a clinically
relevant role in drug disposition, mechanistic insights, and translational applications are still …

From birth, humans coexist and coevolve with trillions of micro-organisms inhabiting most
body surfaces and cavities, referred to as the human microbiome. Advances in sequencing …

Due to its immunomodulatory effects and the limitation in the radiological damage progression,
disease-modifying antirheumatic drugs (DMARDs) work as first-line rheumatoid arthritis (…

Introduction Rheumatoid arthritis (RA) has a huge societal impact due to the high prevalence,
irreversible joint damage and systemic complications. Gut microbiota plays an important …