User profiles for K. T. Zondervan
Krina ZondervanProfessor of Reproductive & Genomic Epidemiology, Oxford University Verified email at wrh.ox.ac.uk Cited by 33233 |
The complex interplay among factors that influence allelic association
KT Zondervan, LR Cardon - Nature Reviews Genetics, 2004 - nature.com
Small effect sizes, common-disease/common-variant versus rare variant influences, biased
single nucleotide polymorphism ascertainment and low linkage disequilibrium have recently …
single nucleotide polymorphism ascertainment and low linkage disequilibrium have recently …
What makes a good case–control study? Design issues for complex traits such as endometriosis
… In a community survey, Zondervan et al. found a prevalence of 24.0% for chronic pelvic pain
in the UK (Zondervan et al., 2001b). A total of 28.3% reported having had chronic pelvic pain…
in the UK (Zondervan et al., 2001b). A total of 28.3% reported having had chronic pelvic pain…
[HTML][HTML] World Endometriosis Research Foundation Endometriosis Phenome and biobanking harmonization project: II. Clinical and covariate phenotype data …
Objective To harmonize the collection of nonsurgical clinical and epidemiologic data relevant
to endometriosis research, allowing large-scale collaboration. Design An international …
to endometriosis research, allowing large-scale collaboration. Design An international …
[HTML][HTML] Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries
…, C Jenkinson, SH Kennedy, KT Zondervan… - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To assess the impact of endometriosis on health-related quality of life (HRQoL)
and work productivity. DESIGN: Multicenter cross-sectional study with prospective …
and work productivity. DESIGN: Multicenter cross-sectional study with prospective …
Data quality control in genetic case-control association studies
This protocol details the steps for data quality assessment and control that are typically carried
out during case-control association studies. The steps described involve the identification …
out during case-control association studies. The steps described involve the identification …
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
Mapping cis- and trans-regulatory effects across multiple tissues in twins
Sequence-based variation in gene expression is a key driver of disease risk. Common
variants regulating expression in cis have been mapped in many expression quantitative trait …
variants regulating expression in cis have been mapped in many expression quantitative trait …
Basic statistical analysis in genetic case-control studies
This protocol describes how to perform basic statistical analysis in a population-based genetic
association case-control study. The steps described involve the (i) appropriate selection …
association case-control study. The steps described involve the (i) appropriate selection …
[HTML][HTML] The architecture of gene regulatory variation across multiple human tissues: the MuTHER study
While there have been studies exploring regulatory variation in one or more tissues, the
complexity of tissue-specificity in multiple primary tissues is not yet well understood. We explore …
complexity of tissue-specificity in multiple primary tissues is not yet well understood. We explore …
Prevalence and incidence of chronic pelvic pain in primary care: evidence from a national general practice database
KT Zondervan, PL Yudkin, MP Vessey… - … Journal of Obstetrics …, 1999 - Wiley Online Library
Objectives To estimate the prevalence and incidence in primary care of chronic pelvic pain in
women in the UK. Design Cross‐sectional analysis of MediPlus UK Primary Care Database…
women in the UK. Design Cross‐sectional analysis of MediPlus UK Primary Care Database…