User profiles for K. Thurley

Kevin Thurley

- Verified email at uni-bonn.de - Cited by 2307

Kay Thurley

- Verified email at bio.lmu.de - Cited by 539

Fundamental properties of Ca2+ signals

K Thurley, A Skupin, R Thul, M Falcke - Biochimica et Biophysica Acta (BBA …, 2012 - Elsevier
… Assuming that these functions are of Hill type (as is the case in most IP 3 R models), a good
measure of the dynamic range of the feedback is the dissociation constant K D . Generally …

[HTML][HTML] Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells

…, LS Morinishi, L Evans, W Ji, CH Hsu, K Thurley… - Nature …, 2016 - nature.com
… , N) calculates the cumulative hypergeometric distribution, with up to k successes in n draws,
without replacement, from a finite population of size N that contains exactly K successes. …

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells

…, N Babel, R Arnold, J Walter, K Thurley… - Nature …, 2018 - nature.com
Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments

…, M de la Rosa, K Hobiger, K Thurley… - Proceedings of the …, 2010 - National Acad Sciences
… deg ), and partial recycling (k rec ). The interaction scheme translates into coupled
reaction–diffusion equations with reactive boundary conditions (SI Text S1: Mathematical Modeling). …

[HTML][HTML] Membrane tension acts through PLD2 and mTORC2 to limit actin network assembly during neutrophil migration

A Diz-Muñoz, K Thurley, S Chintamen… - PLoS …, 2016 - journals.plos.org
… Variation of either the direct or the indirect feedback strength (parameters k i,A and k i,H ,
respectively), in which one of those parameters is held constant at the standard value k i = 20. …

[PDF][PDF] Rhythmic degradation explains and unifies circadian transcriptome and proteome data

S Lück, K Thurley, PF Thaben, PO Westermark - Cell reports, 2014 - cell.com
k and g are the mean rate coefficients, which experience a time modulation described by
cosine-shaped functions with relative (percentage) amplitudes Aprod and Adeg (values …

Reliable Encoding of Stimulus Intensities Within Random Sequences of Intracellular Ca2+ Spikes

K Thurley, SC Tovey, G Moenke, VL Prince… - Science …, 2014 - science.org
Ca 2+ is a ubiquitous intracellular messenger that regulates diverse cellular activities.
Extracellular stimuli often evoke sequences of intracellular Ca 2+ spikes, and spike frequency may …

Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production

C Nazaret, M Heiske, K Thurley, JP Mazat - Journal of theoretical biology, 2009 - Elsevier
… A + B ⟷ C + D d C d t = k AB - CD K eq with k the rate of the forward reaction and K eq the
equilibrium constant of the reaction approximated by K eq = C eq D eq / A eq B eq where X eq …

Dopamine increases the gain of the input-output response of rat prefrontal pyramidal neurons

K Thurley, W Senn, HR Luscher - Journal of …, 2008 - journals.physiology.org
… The value of t j (k) gives the time when the presynaptic neuron j emitted the kth spike,
which is received by neuron i after a delay d = 1 ms. For each connection from a neuron j to a …

Virtual reality systems for rodents

K Thurley, A Ayaz - Current zoology, 2017 - academic.oup.com
Over the last decade virtual reality (VR) setups for rodents have been developed and utilized
to investigate the neural foundations of behavior. Such VR systems became very popular …