Fundamental properties of Ca2+ signals
… Assuming that these functions are of Hill type (as is the case in most IP 3 R models), a good
measure of the dynamic range of the feedback is the dissociation constant K D . Generally …
measure of the dynamic range of the feedback is the dissociation constant K D . Generally …
[HTML][HTML] Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells
… , N) calculates the cumulative hypergeometric distribution, with up to k successes in n draws,
without replacement, from a finite population of size N that contains exactly K successes. …
without replacement, from a finite population of size N that contains exactly K successes. …
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
…, M de la Rosa, K Hobiger, K Thurley… - Proceedings of the …, 2010 - National Acad Sciences
… deg ), and partial recycling (k rec ). The interaction scheme translates into coupled
reaction–diffusion equations with reactive boundary conditions (SI Text S1: Mathematical Modeling). …
reaction–diffusion equations with reactive boundary conditions (SI Text S1: Mathematical Modeling). …
[HTML][HTML] Membrane tension acts through PLD2 and mTORC2 to limit actin network assembly during neutrophil migration
A Diz-Muñoz, K Thurley, S Chintamen… - PLoS …, 2016 - journals.plos.org
… Variation of either the direct or the indirect feedback strength (parameters k i,A and k i,H ,
respectively), in which one of those parameters is held constant at the standard value k i = 20. …
respectively), in which one of those parameters is held constant at the standard value k i = 20. …
[PDF][PDF] Rhythmic degradation explains and unifies circadian transcriptome and proteome data
S Lück, K Thurley, PF Thaben, PO Westermark - Cell reports, 2014 - cell.com
… k and g are the mean rate coefficients, which experience a time modulation described by
cosine-shaped functions with relative (percentage) amplitudes Aprod and Adeg (values …
cosine-shaped functions with relative (percentage) amplitudes Aprod and Adeg (values …
Reliable Encoding of Stimulus Intensities Within Random Sequences of Intracellular Ca2+ Spikes
Ca 2+ is a ubiquitous intracellular messenger that regulates diverse cellular activities.
Extracellular stimuli often evoke sequences of intracellular Ca 2+ spikes, and spike frequency may …
Extracellular stimuli often evoke sequences of intracellular Ca 2+ spikes, and spike frequency may …
Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production
C Nazaret, M Heiske, K Thurley, JP Mazat - Journal of theoretical biology, 2009 - Elsevier
… A + B ⟷ C + D d C d t = k AB - CD K eq with k the rate of the forward reaction and K eq the
equilibrium constant of the reaction approximated by K eq = C eq D eq / A eq B eq where X eq …
equilibrium constant of the reaction approximated by K eq = C eq D eq / A eq B eq where X eq …
Dopamine increases the gain of the input-output response of rat prefrontal pyramidal neurons
… The value of t j (k) gives the time when the presynaptic neuron j emitted the kth spike,
which is received by neuron i after a delay d = 1 ms. For each connection from a neuron j to a …
which is received by neuron i after a delay d = 1 ms. For each connection from a neuron j to a …
Virtual reality systems for rodents
Over the last decade virtual reality (VR) setups for rodents have been developed and utilized
to investigate the neural foundations of behavior. Such VR systems became very popular …
to investigate the neural foundations of behavior. Such VR systems became very popular …