Genetic variants associated with anxiety and stress-related disorders: a genome-wide association study and mouse-model study
Importance Anxiety and stress-related disorders are among the most common mental
disorders. Although family and twin studies indicate that both genetic and environmental factors …
disorders. Although family and twin studies indicate that both genetic and environmental factors …
Not Only for Egg Yolk—Functional and Evolutionary Insights from Expression, Selection, and Structural Analyses of Formica Ant Vitellogenins
…, J Kulmuni, K Dhaygude, K Trontti… - Molecular biology …, 2014 - academic.oup.com
Vitellogenin (Vg), a storage protein, has been extensively studied for its egg-yolk precursor
role, and it has been suggested to be fundamentally involved in caste differences in social …
role, and it has been suggested to be fundamentally involved in caste differences in social …
Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
SN Kurki, P Uvarov, AS Pospelov, K Trontti… - Cerebral …, 2023 - academic.oup.com
The Na-K-2Cl cotransporter NKCC1 is widely expressed in cells within and outside the brain.
However, our understanding of its roles in brain functions throughout development, as well …
However, our understanding of its roles in brain functions throughout development, as well …
Genetic control of myelin plasticity after chronic psychosocial stress
MA Laine, K Trontti, Z Misiewicz, E Sokolowska… - eneuro, 2018 - eneuro.org
Anxiety disorders often manifest in genetically susceptible individuals after psychosocial
stress, but the mechanisms underlying these gene-environment interactions are largely …
stress, but the mechanisms underlying these gene-environment interactions are largely …
[HTML][HTML] A Metatranscriptomic Approach to the Identification of Microbiota Associated with the Ant Formica exsecta
…, S Lindström, H Helanterä, L Sundström, K Trontti - PLoS …, 2013 - journals.plos.org
… Full details of the final ant transcriptome assembly will be published elsewhere (Trontti et al.
unpublished data). The reads that did not match to any ant genomes were BLAST searched …
unpublished data). The reads that did not match to any ant genomes were BLAST searched …
[HTML][HTML] Multi-omics analysis identifies mitochondrial pathways associated with anxiety-related behavior
Stressful life events are major environmental risk factors for anxiety disorders, although not
all individuals exposed to stress develop clinical anxiety. The molecular mechanisms …
all individuals exposed to stress develop clinical anxiety. The molecular mechanisms …
[HTML][HTML] miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment …
J Mingardi, L La Via, P Tornese, G Carini, K Trontti… - Neurobiology of …, 2021 - Elsevier
Converging clinical and preclinical evidence demonstrates that depressive phenotypes are
associated with synaptic dysfunction and dendritic simplification in cortico-limbic …
associated with synaptic dysfunction and dendritic simplification in cortico-limbic …
NF‐E2‐related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin‐1 mutated Alzheimer's …
M Oksanen, I Hyötyläinen, K Trontti, T Rolova… - Glia, 2020 - Wiley Online Library
Alzheimer's disease (AD) is a common dementia affecting a vast number of individuals and
significantly impairing quality of life. Despite extensive research in animal models and …
significantly impairing quality of life. Despite extensive research in animal models and …
[HTML][HTML] Node of Ranvier remodeling in chronic psychosocial stress and anxiety
…, G Mazzini, S Journée, V Alenius, K Trontti… - …, 2023 - nature.com
… k Time spent in the interaction zone during empty and target sessions of the SA test (two-way
repeated ANOVA: group × session F(1,22) = 0.703, p = 0.402; session F(1,22) = 6.111, p = …
repeated ANOVA: group × session F(1,22) = 0.703, p = 0.402; session F(1,22) = 6.111, p = …
Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia
M Koskuvi, Š Lehtonen, K Trontti, M Keuters, YC Wu… - Glia, 2022 - Wiley Online Library
… Kalevi Trontti, Iiris Hovatta performed RNA sequencing analyses and contributed to the
interpretation of the results. Tyrone D. Cannon, Jouko Lönnqvist, Sebastian Therman, Jaana …
interpretation of the results. Tyrone D. Cannon, Jouko Lönnqvist, Sebastian Therman, Jaana …