… While very fast, these k-mer-based approaches do not retain the coherence of the k-mers
along a read, which can reduce specificity, and they cannot easily estimate certain aspects of …

Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects …

Medical error poses an important healthcare burden and a challenge for physicians and
policy makers worldwide. Diagnostic error accounts for a substantial fraction of all medical …

… (K − 1) matrix, where each column corresponds to a contrast between two consecutive β glk
and β gl(k+1) and where we have K − 1 contrasts per lineage for a total of L (K − 1) contrasts. …

Context Diagnostic errors have been associated with bias in clinical reasoning. Empirical
evidence on the cognitive mechanisms underlying biases and effectiveness of educational …

Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain 1 , 2 – 3 . With the proliferation of multi-omics …

… computed with the number of unknown covariates K=0, ie, no latent variables were inferred.
To cluster the real datasets, we inferred an optimal choice of K using the AIC (Additional file 1…

Toward the poles, life on land is increasingly dominated by microorganisms, yet the evolutionary
origin of polar microbiomes remains poorly understood. Here, we use metabarcoding of …

RNA sequencing studies with complex designs and transcript-resolution analyses involve
multiple hypotheses per gene; however, conventional approaches fail to control the false …

Background Literature suggests that patients who display disruptive behaviours in the
consulting room fuel negative emotions in doctors. These emotions, in turn, are said to cause …