In vitro chromosome doubling can be induced by several antimitotic agents. The most
commonly used are colchicine, oryzalin and trifluralin. The process of induced chromosome …

… with the day-to-day demands on practitioners (Van Laere, 2012). There is little recognition of
the … Katrien Van Laere et al. explore the implications in their contribution to this issue of the …

The discovery of the CRISPR/Cas genome-editing system has revolutionized our understanding
of the plant genome. CRISPR/Cas has been used for over a decade to modify plant …

Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …

Importance Amyloid-β positron emission tomography (PET) imaging allows in vivo detection
of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its …

Objective The most widely studied positron emission tomography ligand for in vivo β‐amyloid
imaging is 11 C‐Pittsburgh compound B ( 11 C‐PIB). Its availability, however, is limited by …

These guidelines summarize the current views of the European Association of Nuclear
Medicine Neuroimaging Committee (ENC). The purpose of the guidelines is to assist nuclear …

Emergence of SARS-CoV-2 causing COVID-19 has resulted in hundreds of thousands of
deaths. In search for key targets of effective therapeutics, robust animal models mimicking …

… PET metabolic data acquisition was performed according to the standard clinical protocol
(Van Laere et al., 2006). FDG data were spatially normalized to Montreal Neurological Institute …

[ 18 F]MK-9470 is a selective, high-affinity, inverse agonist (human IC 50 , 0.7 nM) for the
cannabinoid CB1 receptor (CB1R) that has been developed for use in human brain imaging. …