User profiles for K. Van der Heiden

Kim Van der Heiden

Associate professor Erasmus MC
Verified email at erasmusmc.nl
Cited by 3624

Role of nuclear factor κB in cardiovascular health and disease

K Van der Heiden, S Cuhlmann, LA Luong… - Clinical …, 2010 - portlandpress.com
Cardiovascular pathologies are still the primary cause of death worldwide. The molecular
mechanisms behind these pathologies have not been fully elucidated. Unravelling them will …

The effects of stenting on shear stress: relevance to endothelial injury and repair

K Van der Heiden, FJH Gijsen, A Narracott… - Cardiovascular …, 2013 - academic.oup.com
… Kim Van der Heiden , Kim Van der Heiden … Kim Van der Heiden, Frank JH Gijsen, Andrew
Narracott, Sarah Hsiao, Ian Halliday, Julian Gunn, Jolanda J. Wentzel, Paul C. Evans, The …

The role of shear stress on ET-1, KLF2, and NOS-3 expression in the developing cardiovascular system of chicken embryos in a venous ligation model

BCW Groenendijk, K Van der Heiden… - …, 2007 - journals.physiology.org
In this review, the role of wall shear stress in the chicken embryonic heart is analyzed to
determine its effect on cardiac development through regulating gene expression. Therefore, …

Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state

M Zakkar, K Van der Heiden, LA Luong… - … , and vascular biology, 2009 - Am Heart Assoc
Objective— Proinflammatory mediators influence atherosclerosis by inducing adhesion
molecules (eg, VCAM-1) on endothelial cells (ECs) via signaling intermediaries including p38 …

Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical …

…, E Edelman, P Evans, K Van Der Heiden… - European heart …, 2019 - academic.oup.com
… Frank Gijsen, Yuki Katagiri, Peter Barlis, Christos Bourantas, Carlos Collet, Umit Coskun,
Joost Daemen, Jouke Dijkstra, Elazer Edelman, Paul Evans, Kim van der Heiden, Rod Hose …

Primary cilia sensitize endothelial cells for fluid shear stress

BP Hierck, K Van der Heiden… - … dynamics: an official …, 2008 - Wiley Online Library
… primary cilium in a shear stress–dependent fashion (Van der Heiden et al.,2006). In addition,
… , show ciliated EC before and after the onset of atherogenesis (Van der Heiden et al.,2008). …

Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis

K Van der Heiden, BP Hierck, R Krams, R de Crom… - Atherosclerosis, 2008 - Elsevier
Atherosclerosis develops in the arterial system at sites of low as well as low and oscillating
shear stress. Previously, we demonstrated a shear-related distribution of ciliated endothelial …

[HTML][HTML] Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail

…, J Chen, M Ariaans, SE Francis, K Van der Heiden… - Scientific reports, 2017 - nature.com
Blood flow influences atherosclerosis by generating wall shear stress, which alters endothelial
cell (EC) physiology. Low shear stress induces dedifferentiation of EC through a process …

Monocilia on chicken embryonic endocardium in low shear stress areas

K Van der Heiden, BCW Groenendijk… - … dynamics: an official …, 2006 - Wiley Online Library
During cardiovascular development, fluid shear stress patterns change dramatically due to
extensive remodeling. This biomechanical force has been shown to drive gene expression in …

TWIST1 integrates endothelial responses to flow in vascular dysfunction and atherosclerosis

…, SE Francis, PD Weinberg, K van der Heiden… - Circulation …, 2016 - Am Heart Assoc
… Kim van der Heiden Kim van der Heiden … Cuhlmann S, Van der Heiden K, Saliba D,
Tremoleda JL, Khalil M, Zakkar M, Chaudhury H, Luong le A, Mason JC, Udalova I, Gsell W, Jones H…