User profiles for K.N. Manolopoulos
Konstantinos ManolopoulosUniversity of Birmingham Verified email at bham.ac.uk Cited by 3175 |
Gluteofemoral body fat as a determinant of metabolic health
Body fat distribution is an important metabolic and cardiovascular risk factor, because the
proportion of abdominal to gluteofemoral body fat correlates with obesity-associated diseases …
proportion of abdominal to gluteofemoral body fat correlates with obesity-associated diseases …
Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress
Oxidative stress is an important determinant not only in the pathogenesis of Alzheimer's
disease (AD), but also in insulin resistance (InsRes) and diabetic complications. Forkhead box …
disease (AD), but also in insulin resistance (InsRes) and diabetic complications. Forkhead box …
Oxygenation of adipose tissue: A human perspective
…, RLJ van Meijel, KN Manolopoulos… - Acta …, 2020 - Wiley Online Library
Obesity is a complex disorder of excessive adiposity, and is associated with adverse health
effects such as cardiometabolic complications, which are to a large extent attributable to …
effects such as cardiometabolic complications, which are to a large extent attributable to …
[PDF][PDF] Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
…, P Nightingale, GA Wallis, KN Manolopoulos… - Cell reports, 2019 - cell.com
Nicotinamide adenine dinucleotide (NAD + ) is modulated by conditions of metabolic stress
and has been reported to decline with aging in preclinical models, but human data are …
and has been reported to decline with aging in preclinical models, but human data are …
Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications
…, KN Manolopoulos, SE McQuaid, P Valet, KN Frayn… - Diabetes, 2014 - Am Diabetes Assoc
Upper- and lower-body fat depots exhibit opposing associations with obesity-related metabolic
disease. We defined the relationship between DEXA-quantified fat depots and diabetes/…
disease. We defined the relationship between DEXA-quantified fat depots and diabetes/…
[HTML][HTML] Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: a longitudinal study based on a United Kingdom …
Background Androgen excess is a defining feature of polycystic ovary syndrome (PCOS),
which affects 10% of women and represents a lifelong metabolic disorder, with increased risk …
which affects 10% of women and represents a lifelong metabolic disorder, with increased risk …
Cardiometabolic disease burden and steroid excretion in benign adrenal tumors: a cross-sectional multicenter study
…, WF Young Jr, KN Manolopoulos… - Annals of internal …, 2022 - acpjournals.org
Background: Benign adrenal tumors are commonly discovered on cross-sectional imaging.
Mild autonomous cortisol secretion (MACS) is regularly diagnosed, but its effect on …
Mild autonomous cortisol secretion (MACS) is regularly diagnosed, but its effect on …
AKR1C3-mediated adipose androgen generation drives lipotoxicity in women with polycystic ovary syndrome
…, M Walsh, AE Taylor, KN Manolopoulos… - The Journal of …, 2017 - academic.oup.com
Context Polycystic ovary syndrome (PCOS) is a prevalent metabolic disorder occurring in
up to 10% of women of reproductive age. PCOS is associated with insulin resistance and …
up to 10% of women of reproductive age. PCOS is associated with insulin resistance and …
Mobilising vitamin D from adipose tissue: The potential impact of exercise
…, JA Betts, M Hewison, KN Manolopoulos… - Nutrition …, 2019 - Wiley Online Library
Vitamin D is lipophilic and accumulates substantially in adipose tissue. Even without
supplementation, the amount of vitamin D in the adipose of a typical adult is equivalent to several …
supplementation, the amount of vitamin D in the adipose of a typical adult is equivalent to several …
[HTML][HTML] Distinct inflammatory signatures of upper and lower body adipose tissue and adipocytes in women with normal weight or obesity
…, R Dineen, EE Blaak, KN Manolopoulos… - Frontiers in …, 2023 - frontiersin.org
Introduction Upper and lower body fat accumulation poses an opposing obesity-related
cardiometabolic disease risk. Depot-differences in subcutaneous adipose tissue (SAT) function …
cardiometabolic disease risk. Depot-differences in subcutaneous adipose tissue (SAT) function …