Atomic-resolution protein structure determination by cryo-EM

KM Yip, N Fischer, E Paknia, A Chari, H Stark - Nature, 2020 - nature.com
Single-particle electron cryo-microscopy (cryo-EM) is a powerful method for solving the three-dimensional
structures of biological macromolecules. The technological development of …

Breaking the next Cryo-EM resolution barrier–Atomic resolution determination of proteins!

KM Yip, N Fischer, E Paknia, A Chari, H Stark - BioRxiv, 2020 - biorxiv.org
Single particle cryo-EM is a powerful method to solve the three-dimensional structures of
biological macromolecules. The technological development of electron microscopes, detectors, …

[HTML][HTML] Impact of COVID-19 pandemic on school-aged children's physical activity, screen time, and Sleep in Hong Kong: a cross-sectional repeated Measures Study

HK So, GT Chua, KM Yip, KTS Tung, RS Wong… - International Journal of …, 2022 - mdpi.com
Despite concerns about the negative effects of social distancing and prolonged school closures
on children’s lifestyle and physical activity (PA) during the COVID-19 pandemic, robust …

[PDF][PDF] COVID-19 vaccines versus pediatric hospitalization

JSR Duque, D Leung, KM Yip, DHL Lee, H So… - Cell Reports …, 2023 - cell.com
Vaccine effectiveness of BNT162b2 and CoronaVac against COVID-19-associated hospitalization
and moderate-to-severe disease due to SARS-CoV-2 Omicron BA.2 is studied from …

[HTML][HTML] Effectiveness of BNT162b2 and CoronaVac in children and adolescents against SARS-CoV-2 infection during Omicron BA. 2 wave in Hong Kong

D Leung, JS Rosa Duque, KM Yip, HK So… - Communications …, 2023 - nature.com
Background The SARS-CoV-2 Omicron BA.2 subvariant replaced BA.1 globally in early 2022,
and caused an unprecedented tsunami of cases in Hong Kong, resulting in the collapse of …

Ginseng ameliorates exercise-induced fatigue potentially by regulating the gut microbiota

SS Zhou, J Zhou, JD Xu, H Shen, M Kong, KM Yip… - Food & Function, 2021 - pubs.rsc.org
The therapeutic effects of water extract of ginseng (WEG) on exercise-induced fatigue (EF)
have been reported in several previous studies, but the molecular mechanisms involved …

[HTML][HTML] Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy

…, T Yi, J Xu, J Wang, JJ Qin, Q Chen, KM Yip… - … Pharmaceutica Sinica B, 2021 - Elsevier
Mitochondria as a signaling platform play crucial roles in deciding cell fate. Many classic
anticancer agents are known to trigger cell death through induction of mitochondrial damage. …

Characterization of chemical component variations in different growth years and tissues of Morindae Officinalis Radix by integrating metabolomics and glycomics

KM Yip, J Xu, SS Zhou, YM Lau, QL Chen… - Journal of agricultural …, 2019 - ACS Publications
Morindae Officinalis Radix (MOR), the dried root of Morinda officinalis FC How (Rubiaceae),
is a popular food supplement in southeastern China for bone protection, andrological, and …

[PDF][PDF] Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots

K Singh, G Bunzel, B Graf, KM Yip, M Neumann-Schaal… - Cell, 2023 - cell.com
Fatty acids (FAs) play a central metabolic role in living cells as constituents of membranes,
cellular energy reserves, and second messenger precursors. A 2.6 MDa FA synthase (FAS), …

[HTML][HTML] Age-and sex-specific physical fitness reference and association with body mass index in Hong Kong Chinese schoolchildren

KM Yip, SWS Wong, GT Chua, HK So, FK Ho… - International Journal of …, 2022 - mdpi.com
There is lacking a population-based study on the fitness level of Hong Kong schoolchildren,
and it seems that increasing childhood obesity prevalence has shifted the classification of …