10.7554/eLife.26476.001 Immune cells infiltrating tumors can have important impact on tumor
progression and response to therapy. We present an efficient algorithm to simultaneously …

The roles of NK cells in human melanoma remain only partially understood. We characterized
NK cells from peripheral blood ex vivo by flow cytometry obtained from late stage (III/IV) …

Increased density of tumor-associated lymphatic vessels correlates with poor patient
survival in melanoma and other cancers, yet lymphatic drainage is essential for initiating an …

The understanding of the role of B cells in patients with solid tumors remains insufficient. We
found that circulating B cells produced TNFα and/or IL-6, associated with unresponsiveness …

Simple Summary We investigated the feasibility and immunogenicity of an autologous
Dendritic Cell (DC) vaccine pulsed with peptide neoantigens in combination with a standard of …

Leishmania major (L. major) parasites are intracellular parasites belong to the Trypanosomatidae
family and are the causative agent of cutaneous leishmaniasis. This disease affects …

Since 1994, a population‐based study of frontotemporal dementia (FTD) in The Netherlands
has aimed to ascertain all patients with FTD, and first prevalence estimates based on 74 …

Objective To examine the clinical value of neurofilament light chain (NfL) and the phospho-tau/total
tau ratio (p/t-tau) across the entire frontotemporal dementia (FTD) spectrum in a large…

Introduction Trials to test disease-modifying treatments for frontotemporal dementia are eagerly
awaited and sensitive instruments to assess potential treatment effects are increasingly …

Background Semantic dementia (SD) is a neurodegenerative disorder characterised by
progressive language problems falling within the clinicopathological spectrum of frontotemporal …