A quick route to multiple highly potent SARS‐CoV‐2 main protease inhibitors
…, HE Ward, YJ Sheng, JC Hsu, KC Kratch… - …, 2021 - Wiley Online Library
The COVID‐19 pathogen, SARS‐CoV‐2, requires its main protease (SC2M Pro ) to digest
two of its translated long polypeptides to form a number of mature proteins that are essential …
two of its translated long polypeptides to form a number of mature proteins that are essential …
Bepridil is potent against SARS-CoV-2 in vitro
…, KS Yang, AK Drelich, KC Kratch… - Proceedings of the …, 2021 - National Acad Sciences
Guided by a computational docking analysis, about 30 Food and Drug Administration/European
Medicines Agency (FDA/EMA)-approved small-molecule medicines were characterized …
Medicines Agency (FDA/EMA)-approved small-molecule medicines were characterized …
Expressed protein ligation without intein
Proteins with a functionalized C-terminus such as a C-terminal thioester are key to the synthesis
of larger proteins via expressed protein ligation. They are usually made by recombinant …
of larger proteins via expressed protein ligation. They are usually made by recombinant …
Tuning interfacial electron transfer in nanostructured cuprous oxide photoelectrochemical cells with charge-selective molecular coatings
KM Haynes, KC Kratch, SD Stovall… - … Applied Materials & …, 2015 - ACS Publications
The coating of nanostructured films of cuprous oxide with electroactive molecules strongly
affects their photoelectrochemical performance in nonaqueous photocells, with photocurrent …
affects their photoelectrochemical performance in nonaqueous photocells, with photocurrent …
A speedy route to multiple highly potent SARS-CoV-2 main protease inhibitors
…, HE Ward, YJ Sheng, JC Hsu, KC Kratch… - bioRxiv, 2020 - biorxiv.org
The COVID-19 pathogen, SARS-CoV-2, requires its main protease (SC2M Pro ) to digest two
of its translated polypeptides to form a number of mature proteins that are essential for viral …
of its translated polypeptides to form a number of mature proteins that are essential for viral …
Targeting the SARS-CoV-2 Main Protease to Repurpose Drugs for COVID-19 (preprint)
EC Vatansever, KS Yang, KC Kratch, A Drelich… - 2020 - pesquisa.bvsalud.org
Guided by a computational docking analysis, about 30 FDA/EMA-approved small molecule
medicines were characterized on their inhibition of the SARS-CoV-2 main protease (MPro). …
medicines were characterized on their inhibition of the SARS-CoV-2 main protease (MPro). …
Chemical Biology Approaches to Drug Design: Activated Cysteine-Like Protein Ligation, SARS-CoV-2 Drug Repurposing and Hypoxia Activated Prodrug Triggers
KC Kratch - 2021 - search.proquest.com
… My Father, Tim Kratch, for his unconditional … Kratch for her pragmaticism, reminding me
to always weigh the possible outcomes and to think before I act. And my Brother, Joe Kratch, …
to always weigh the possible outcomes and to think before I act. And my Brother, Joe Kratch, …
A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors
…, B Sankaran, HE Ward, YJ Sheng, JC Hsu, KK Kratch… - 2020 - pesquisa.bvsalud.org
The COVID-19 pathogen, SARS-CoV-2, requires its main protease (SC2MPro) to digest two
of its translated polypeptides to form a number of mature proteins that are essential for viral …
of its translated polypeptides to form a number of mature proteins that are essential for viral …
A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors (preprint)
…, B Sankaran, HE Ward, YJ Sheng, JC Hsu, KK Kratch… - 2020 - pesquisa.bvsalud.org
The COVID-19 pathogen, SARS-CoV-2, requires its main protease (SC2MPro) to digest two
of its translated polypeptides to form a number of mature proteins that are essential for viral …
of its translated polypeptides to form a number of mature proteins that are essential for viral …
SITE-SPECIFIC PROTEIN FUNCTIONALIZATION USING ACTIVATED CYSTEINE BASED CHEMICAL BIOLOGY METHODS
Y Qiao - 2021 - oaktrust.library.tamu.edu
… The synthesis of dipeptides and the following ACPL reactions with propargylamine shown
in Chapter II, 2.1 were done by Kaci Kratch in Liu’s research group. The RNAseH expression, …
in Chapter II, 2.1 were done by Kaci Kratch in Liu’s research group. The RNAseH expression, …