User profiles for Kaiqiang You

Kaiqiang You

Peking University
Verified email at pku.edu.cn
Cited by 348

PhaSepDB: a database of liquid–liquid phase separation related proteins

K You, Q Huang, C Yu, B Shen, C Sevilla… - Nucleic acids …, 2020 - academic.oup.com
It's widely appreciated that liquid–liquid phase separation (LLPS) underlies the formation of
membraneless organelles, which function to concentrate proteins and nucleic acids. In the …

[HTML][HTML] p53 β-hydroxybutyrylation attenuates p53 activity

K Liu, F Li, Q Sun, N Lin, H Han, K You, F Tian… - Cell death & …, 2019 - nature.com
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PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information

…, H Xie, T Chen, P Zhu, X Xu, K You… - Nucleic Acids …, 2023 - academic.oup.com
Phase separation (PS) proteins form droplets to regulate myriad membraneless organelles (MLOs)
and cellular pathways such as transcription, signaling transduction and protein …

[HTML][HTML] Quantifying the phase separation property of chromatin-associated proteins under physiological conditions using an anti-1, 6-hexanediol index

M Shi, K You, T Chen, C Hou, Z Liang, M Liu, J Wang… - Genome biology, 2021 - Springer
Background Liquid-liquid phase separation (LLPS) is an important organizing principle for
biomolecular condensation and chromosome compartmentalization. However, while many …

[HTML][HTML] OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity

F Li, Q Sun, K Liu, L Zhang, N Lin, K You, M Liu… - Nature …, 2020 - nature.com
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Proteome-scale analysis of phase-separated proteins in immunofluorescence images

C Yu, B Shen, K You, Q Huang, M Shi… - Briefings in …, 2021 - academic.oup.com
Phase separation is an important mechanism that mediates the spatial distribution of proteins
in different cellular compartments. While phase-separated proteins share certain sequence …

Marsdeniae tenacissimae extract (MTE) suppresses cell proliferation by attenuating VEGF/VEGFR2 interactions and promotes apoptosis through regulating PKC …

C Bing-Yu, C Dong, LYU Jian-Xin, LI Kai-Qiang… - Chinese journal of …, 2016 - Elsevier
Marsdeniae tenacissimae extract (MTE), commonly known as Xiao-Ai-Ping in China, is a
traditional Chinese herb medicine capable of inhibiting proliferation and metastasis and …

[PDF][PDF] Quantifying liquid-liquid phase separation property of chromatin under physiological conditions using Hi-MS and Hi-C

M Shi, K You, C Hou, T Chen, Z Liang, M Liu, J Wang… - bioRxiv, 2020 - academia.edu
Background: Liquid–liquid phase separation (LLPS) is an important organizing principle for
biomolecular condensation and chromosome compartmentalization. However, while many …

[HTML][HTML] CBCT-based synthetic CT generated using CycleGAN with HU correction for adaptive radiotherapy of nasopharyngeal carcinoma

C Jihong, Q Kerun, C Kaiqiang, Z Xiuchun, Z Yimin… - Scientific Reports, 2023 - nature.com
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Deep-learning enables proteome-scale identification of phase-separated protein candidates from immunofluorescence images

C Yu, B Shen, Q Huang, M Shi, K You, C Wu, Y Chen… - bioRxiv, 2019 - biorxiv.org
Intrinsically disordered region (IDR) analysis has been widely used in the screening of
phase-separated proteins. However, the precise sequences determining phase separation …