Purpose Although early menopause frequently occurs in female cancer patients after
chemotherapy (CTx), bone marrow (BM) transplantation (BMT) has been linked to an unexplained …

Reproductive aging in female mammals is an irreversible process associated with declining
oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of …

Increased meiotic spindle abnormalities and aneuploidy in oocytes of women of advanced
maternal ages lead to elevated rates of infertility, miscarriage, and trisomic conceptions. …

Age‐related ovarian failure in women heralds the transition into postmenopausal life, which
is characterized by a loss of fertility and increased risk for cardiovascular disease, …

The female reproductive axis is the first major organ system of the body to fail with advancing
age. In addition to a permanent cessation of fertile potential, the loss of cyclic ovarian …

Activated immune cells secrete proinflammatory cytokines such as tumor necrosis factor alpha
(TNF-alpha), interferon–gamma (IFN-gamma) and Fas ligand (FasL) and these cytokines …

Trophoblasts provide a model to investigate fundamental mechanisms of stem cell
differentiation, but the availability of trophoblast stem cell lines is limited. Here we report the …

OBJECTIVE: To determine whether granulocyte colony-stimulating factor (G-CSF), stem cell
factor (SCF), or vascular endothelial growth factor (VEGF) improve the outcome of ovarian …

Activation of the aryl hydrocarbon receptor (AHR) by polycyclic aromatic hydrocarbons (PAH),
a ubiquitous class of environmental and occupational biohazards, accelerates germ cell …

Defects in placental development lead to pregnancies at risk for miscarriage and intrauterine
growth retardation and are associated with preeclampsia, a leading cause of maternal …