[HTML][HTML] Trained immunity in diabetes and hyperlipidemia: Emerging opportunities to target cardiovascular complications and design new therapies

KA Robinson, N Akbar, K Baidžajevas… - The FASEB …, 2023 - ncbi.nlm.nih.gov
Some metabolic diseases, such as diabetes and hyperlipidemia, are associated with a state
of inflammation, which adversely affects cardiovascular health. Emerging evidence …

[HTML][HTML] Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability

E Hadadi, B Zhang, K Baidžajevas, N Yusof… - Scientific Reports, 2016 - nature.com
Monocytes play a central role in regulating inflammation in response to infection or injury, and
during auto-inflammatory diseases. Human blood contains classical, intermediate and non…

Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion

…, RC Bauer, S Hamby, SK Suvarna, K Baidžajevas… - Science …, 2019 - science.org
Macrophages drive atherosclerotic plaque progression and rupture; hence, attenuating their
atherosclerosis-inducing properties holds promise for reducing coronary heart disease (…

Macrophage polarisation associated with atherosclerosis differentially affects their capacity to handle lipids

K Baidžajevas, É Hadadi, B Lee, J Lum, F Shihui… - Atherosclerosis, 2020 - Elsevier
Background and aims Lipid-rich foam cell macrophages drive atherosclerosis via several
mechanisms, including inflammation, lipid uptake, lipid deposition and plaque vulnerability. …

Genome-wide association and functional analyses identify CASC20 and KIF26B as target loci in heterotopic ossification

…, M Koprulu, L Southam, I Bellantuono, K Baidžajevas… - bioRxiv, 2019 - biorxiv.org
Heterotopic ossification (HO) is bone formation that occurs after trauma within tissues that
do not normally have the property of ossification, resulting in pain and disability. The genetic …

[PDF][PDF] Dynamic regulation of endothelial P2X7 receptors by blood flow patterns associated with atherosclerosis

JP Green - 2016 - etheses.whiterose.ac.uk
… ' group for use of their mRNA isolated from endothelial cells from the porcine aorta; and by
Kajus Baidžajevas and Yang Li who gladly shared their isolated peripheral blood monocytes. …

[PDF][PDF] Myeloid TRIB1 alters tumour microenvironment and breast tumour growth

T Kim - 2020 - etheses.whiterose.ac.uk
… at the start of PhD, Dr Jessica Johnston, Haider Al-Janabi, Mohammed Ridha Moamin, Kajus
Baidžajevas, Yang Li, and Dr Ming Yang for their helped to develop lab skills and start the …