User profiles for Kalin H. Vetsigian

Kalin Vetsigian

Assistant Professor of Bacteriology, University of Wisconsin-Madison
Verified email at wisc.edu
Cited by 2824

[HTML][HTML] Inhibitory interactions promote frequent bistability among competing bacteria

ES Wright, KH Vetsigian - Nature communications, 2016 - nature.com
It is largely unknown how the process of microbial community assembly is affected by the
order of species arrival, initial species abundances and interactions between species. A …

Stochastic exits from dormancy give rise to heavy‐tailed distributions of descendants in bacterial populations

ES Wright, KH Vetsigian - Molecular ecology, 2019 - Wiley Online Library
Variance in reproductive success is a major determinant of the degree of genetic drift in a
population. While many plants and animals exhibit high variance in their number of progeny, …

Multi-stable bacterial communities exhibit extreme sensitivity to initial conditions

ES Wright, R Gupta, KH Vetsigian - FEMS Microbiology Ecology, 2021 - academic.oup.com
Microbial communities can have dramatically different compositions even among similar
environments. This might be due to the existence of multiple alternative stable states, yet there …

DesignSignatures: a tool for designing primers that yields amplicons with distinct signatures

ES Wright, KH Vetsigian - Bioinformatics, 2016 - academic.oup.com
For numerous experimental applications, PCR primers must be designed to efficiently
amplify a set of homologous DNA sequences while giving rise to amplicons with maximally …

[HTML][HTML] Chemical ecosystem selection on mineral surfaces reveals long-term dynamics consistent with the spontaneous emergence of mutual catalysis

…, ST Saghafi, J Cosby, T Sankari, K Vetsigian… - Life, 2019 - mdpi.com
How did chemicals first become organized into systems capable of self-propagation and
adaptive evolution? One possibility is that the first evolvers were chemical ecosystems localized …

[HTML][HTML] Quality filtering of Illumina index reads mitigates sample cross-talk

ES Wright, KH Vetsigian - BMC genomics, 2016 - Springer
Background Multiplexing multiple samples during Illumina sequencing is a common
practice and is rapidly growing in importance as the throughput of the platform increases. …

Diverse modes of eco-evolutionary dynamics in communities of antibiotic-producing microorganisms

K Vetsigian - Nature Ecology & Evolution, 2017 - nature.com
Whether and how toxin-mediated interactions contribute to diversity generation and maintenance
has been a long-standing puzzle. A recent theoretical work has demonstrated that the …

[BOOK][B] Collective evolution of biological and physical systems

KH Vetsigian - 2005 - search.proquest.com
I study the evolution of solidification fronts propagating in undercooled liquids, the evolution
of microbial communities through diversification fronts propagating along microbial genomes…

Counteraction of antibiotic production and degradation stabilizes microbial communities

ED Kelsic, J Zhao, K Vetsigian, R Kishony - Nature, 2015 - nature.com
A major challenge in theoretical ecology is understanding how natural microbial communities
support species diversity 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , and in particular how antibiotic-producing…

[HTML][HTML] Structure and Evolution of Streptomyces Interaction Networks in Soil and In Silico

K Vetsigian, R Jajoo, R Kishony - PLoS biology, 2011 - journals.plos.org
Soil grains harbor an astonishing diversity of Streptomyces strains producing diverse secondary
metabolites. However, it is not understood how this genotypic and chemical diversity is …