Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome
Noonan syndrome is a developmental disorder characterized by short stature, facial
dysmorphia, congenital heart defects and skeletal anomalies 1 . Increased RAS-mitogen-activated …
dysmorphia, congenital heart defects and skeletal anomalies 1 . Increased RAS-mitogen-activated …
An orthosteric inhibitor of the Ras-Sos interaction
Mimics of α-helices on protein surfaces have emerged as powerful reagents for antagonizing
protein-protein interactions, which are difficult to target with small molecules. Here we …
protein-protein interactions, which are difficult to target with small molecules. Here we …
[PDF][PDF] Biofertilizers, impact on soil fertility and crop productivity under sustainable agriculture.
KK Yadav, SS Smritikana Sarkar - 2019 - researchgate.net
Biofertilizers, a sustainable eco-friendly agricultural approach to crop improvement are used
to supplement chemical fertilizers mainly to maintain soil fertility. Continuous application of …
to supplement chemical fertilizers mainly to maintain soil fertility. Continuous application of …
[PDF][PDF] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource (https://…
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource (https://…
[HTML][HTML] Multidrug resistant Enterobacteriaceae and extended spectrum β-lactamase producing Escherichia coli: a cross-sectional study in National Kidney Center …
KK Yadav, N Adhikari, R Khadka, AD Pant… - … resistance and infection …, 2015 - Springer
Background Emergence of antibacterial resistance and production of Extended spectrum β-lactamases
(ESBLs) are responsible for the frequently observed empirical therapy failures. …
(ESBLs) are responsible for the frequently observed empirical therapy failures. …
Integrated nanoscale deterministic lateral displacement arrays for separation of extracellular vesicles from clinically-relevant volumes of biological samples
Extracellular vesicles (EVs) offer many opportunities in early-stage disease diagnosis,
treatment monitoring, and precision therapy owing to their high abundance in bodily fluids, …
treatment monitoring, and precision therapy owing to their high abundance in bodily fluids, …
[HTML][HTML] Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences
Racial disparities in prostate cancer have not been well characterized on a genomic level.
Here we show the results of a multi-institutional retrospective analysis of 1,152 patients (596 …
Here we show the results of a multi-institutional retrospective analysis of 1,152 patients (596 …
[HTML][HTML] Breakthroughs and applications of organ-on-a-chip technology
…, SS Yadav, AV Cherian, TK Pandita, K Shameer… - Cells, 2022 - mdpi.com
Organ-on-a-chip (OOAC) is an emerging technology based on microfluid platforms and in
vitro cell culture that has a promising future in the healthcare industry. The numerous …
vitro cell culture that has a promising future in the healthcare industry. The numerous …
Sublethal exposure of heavy metals induces micronuclei in fish, Channa punctata
KK Yadav, SP Trivedi - Chemosphere, 2009 - Elsevier
Present studies were designed to evaluate toxic potential of three common heavy metals,
adequately present in agro-industrial effluents, viz. mercury, arsenic and copper using in vivo …
adequately present in agro-industrial effluents, viz. mercury, arsenic and copper using in vivo …
[HTML][HTML] The use of biomarkers in prostate cancer screening and treatment
Prostate cancer screening and diagnosis has been guided by prostate-specific antigen
levels for the past 25 years, but with the most recent US Preventive Services Task Force …
levels for the past 25 years, but with the most recent US Preventive Services Task Force …