Occupancy of the T-cell receptor complex does not appear to be a sufficient stimulus to
induce a T-cell-mediated immune response. Increasing evidence suggests that cognate cell-cell …

B cell immunoglobulin production is regulated by helper T cells through direct interaction
and secreted cytokines. In the present study, we functionally analyzed CD27 in cord and …

A prospective multicenter trial of 119 children 1 to 18 years of age with newly diagnosed
aplastic anemia (AA) was conducted, comparing treatment using antithymocyte globulin (ATG), …

Point mutations of D835/I836 of the FLT3 gene have been reported in adult acute myeloid
leukemia (AML), but not in pediatric AML or acute lymphoblastic leukemia (ALL). FLT3-D835/…

Early T‐cell precursor acute lymphoblastic leukaemia (ETP‐ALL) is a recently identified
subtype of T‐ALL with distinctive gene expression and cell marker profiles, poor response to …

The improved outcome of acquired aplastic anemia (AA) has revealed later complications,
such as myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML). We …

Bcr-Abl kinase is known to reverse apoptosis of cytokine-dependent cells due to cytokine
deprivation, although it has been controversial whether chronic myeloid leukemia (CML) …

In this paper, we examined in detail the ability of anti-1F7 to modulate 1F7 (CD26) surface
expression as well as analyzed the functional relationship between the surface expression of …

… Shunji Igarashi, Atsushi Manabe, Akira Ohara, Masaaki Kumagai, Tomohiro Saito, Yuri
Okimoto, Takehiko Kamijo, Keiichi Isoyama, Michiko Kajiwara, Manabu Sotomatsu, Ken-ichi …

Background: Evidence of poor inhibition in attention deficit hyperactivity disorder (ADHD)
comes primarily from neuropsychological tasks and neuroimaging studies, many of which have …