Polycomb-repressive complex 1 (PRC1) has a central role in the regulation of heritable gene
silencing during differentiation and development. PRC1 recruitment is generally attributed …

Transcription factors, such as Oct4, are critical for establishing and maintaining pluripotent
cell identity. Whereas the genomic locations of several pluripotency transcription factors have …

DNA double-strand break (DSB) repair by nonhomologous end joining (NHEJ) requires the
assembly of several proteins on DNA ends. Although biochemical studies have elucidated …

Polycomb Repressor Complexes (PRCs) are important regulators of embryogenesis. In
embryonic stem (ES) cells many genes that regulate subsequent stages in development are …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes coronavirus
disease 2019 (COVID‐19), which may result in acute respiratory distress syndrome (ARDS), …

Transcription regulation involves enzyme-mediated changes in chromatin structure. Here,
we describe a novel mode of histone crosstalk during gene silencing, in which histone H2A …

Microtubule plus-end tracking proteins (+TIPs) are structurally and functionally diverse factors
that accumulate at the growing microtubule plus-ends, connect them to various cellular …

Embryonic stem (ES) cell self-renewal is regulated by transcription factors, including Oct4,
Sox2, and Nanog. A number of additional transcriptional regulators of ES cell self-renewal …

Histone chaperones are involved in a variety of chromatin transactions. By a proteomics
survey, we identified the interaction networks of histone chaperones ASF1, CAF1, HIRA, and …

Embryonic stem (ES) cell self‐renewal efficiency is determined by the Nanog protein level.
However, the protein partners of Nanog that function to direct self‐renewal are unclear. Here, …