Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson’s
disease, dementia with Lewy bodies, and multiple system atrophy. This provides an …

Objective To assess whether risk factors for Parkinson disease and dementia with Lewy
bodies increase rate of defined neurodegenerative disease in idiopathic rapid eye movement (…

We identified association of restless legs syndrome (RLS) with PTPRD at 9p23–24 in 2,458
affected individuals and 4,749 controls from Germany, Austria, Czechia and Canada. Two …

Background and aim Narcolepsy is an uncommon hypothalamic disorder of presumed
autoimmune origin that usually requires lifelong treatment. This paper aims to provide evidence‐…

Recent advances in the identification of susceptibility genes and environmental exposures
provide broad support for a post-infectious autoimmune basis for narcolepsy/hypocretin (…

Objectives We aimed to provide a consensus statement by the International Rapid Eye
Movement Sleep Behavior Disorder Study Group (IRBD-SG) on devising controlled active …

Background Restless legs syndrome is a prevalent chronic neurological disorder with
potentially severe mental and physical health consequences. Clearer understanding of the …

The aim of this European initiative is to facilitate a structured discussion to improve the next
edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter …

Restless legs syndrome (RLS) is a sensorimotor disorder with an age-dependent prevalence
of up to 10% in the general population above 65 years of age. Affected individuals suffer …

For generations, the evaluation of speech abnormalities in neurodegenerative disorders
such as Parkinson’s disease (PD) has been limited to perceptual tests or user-controlled …