Chinese hamster ovary (CHO) cells are widely used for biopharmaceutical protein production.
One challenge limiting CHO cell productivity is apoptosis stemming from cellular stress …

Pooled CRISPR screens have been widely applied to mammalian and other organisms to
elucidate the interplay between genes and phenotypes of interest. The most popular method …

Chinese hamster ovary (CHO) cells are the preferred workhorse for the biopharmaceutical
industry, and CRISPR/Cas9 has proven powerful for generating targeted gene perturbations …

Genome editing has become an increasingly important aspect of Chinese Hamster Ovary (
CHO CHO ) cell line engineering for improving production of recombinant protein therapeutics…

Media and feed optimization have fueled many-fold improvements in mammalian
biopharmaceutical production, but genome editing offers an emerging avenue for further enhancing …

Chinese hamster ovary (CHO) cells are the preferred mammalian host cells for therapeutic
protein production that have been extensively engineered to possess the desired attributes …

The dominant method for generating Chinese hamster ovary (CHO) cell lines that produce
high titers of biotherapeutic proteins utilizes selectable markers such as dihydrofolate …

As the era of omics continues to expand with increasing ubiquity and success in both
academia and industry, omics-based experiments are becoming commonplace in industrial …

Chinese hamster ovary (CHO) cells are widely used for producing biopharmaceuticals, and
engineering gene expression in CHO is key to improving drug quality and affordability. …

Advances in CRISPR (clustered regularly interspaced short palindromic repeats) technology
have transformed the field of genome engineering, offering new opportunities for targeted …