Association analysis identifies 65 new breast cancer risk loci

…, U Eilber, JD French, X Qing Chen, L Fachal, K McCue… - Nature, 2017 - nature.com
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …

[HTML][HTML] Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice

V Randall, K McCue, C Roberts… - The Journal of …, 2009 - Am Soc Clin Investig
… Authorship note: Victoria Randall and Karen McCue contributed equally to this work. …
Authorship note: Victoria Randall and Karen McCue contributed equally to this work. …

Environmental contamination with rhinovirus and transfer to fingers of healthy individuals by daily life activity

B Winther, K McCue, K Ashe, JR Rubino… - Journal of medical …, 2007 - Wiley Online Library
Rhinovirus infection may be acquired by inoculation of virus on fingertips to conjunctiva or
nose (self‐inoculation). The virus contaminating the fingertips may come from hand contact …

[HTML][HTML] CRISPR screens identify gene targets at breast cancer risk loci

…, JM Paynter, D Black, A Civitarese, K McCue… - Genome biology, 2023 - Springer
Background Genome-wide association studies (GWAS) have identified > 200 loci associated
with breast cancer risk. The majority of candidate causal variants are in non-coding regions …

[HTML][HTML] Functional mechanisms underlying pleiotropic risk alleles at the 19p13. 1 breast–ovarian cancer susceptibility locus

K Lawrenson, S Kar, K McCue, K Kuchenbaeker… - Nature …, 2016 - nature.com
A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here
we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 …

Virucidal efficacy of disinfectant actives against feline calicivirus, a surrogate for norovirus, in a short contact time

K Whitehead, KA McCue - American journal of infection control, 2010 - Elsevier
BACKGROUND: Among other measures, handwashing and targeted disinfection are important
in preventing and controlling norovirus outbreaks. Presently, there are a limited number …

A critical evaluation of methicillin-resistant Staphylococcus aureus and other bacteria of medical interest on commonly touched household surfaces in relation to …

E Scott, S Duty, K McCue - American Journal of Infection Control, 2009 - Elsevier
BACKGROUND: We sought to characterize and quantify bacteria of medical interest on
commonly touched household surfaces and to evaluate predictors such as employment, day …

[PDF][PDF] Polymorphisms in a putative enhancer at the 10q21. 2 breast cancer risk locus regulate NRBF2 expression

H Darabi, K McCue, J Beesley, K Michailidou… - The American Journal of …, 2015 - cell.com
Genome-wide association studies have identified SNPs near ZNF365 at 10q21.2 that are
associated with both breast cancer risk and mammographic density. To identify the most likely …

[HTML][HTML] A 28 day clinical assessment of a lactic acid-containing antimicrobial intimate gel wash formulation on skin tolerance and impact on the vulvar microbiome

E Bruning, Y Chen, KA McCue, JR Rubino… - Antibiotics, 2020 - mdpi.com
While intimate feminine hygiene products are widely used as part of daily cleansing routines,
little is known about how these products impact the vulvovaginal area and its microbiome …

[HTML][HTML] A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development

S Payne, MJ Burney, K McCue, N Popal… - Developmental …, 2015 - Elsevier
CHARGE syndrome is caused by spontaneous loss-of-function mutations to the ATP-dependant
chromatin remodeller chromodomain-helicase-DNA-binding protein 7 (CHD7). It is …