User profiles for Karen Oróstica
 | Karen OrósticaInstituto de Investigación Interdisciplinaria, Vicerrectoría Académica, Universidad de Talca … Verified email at utalca.cl Cited by 86 |
chromPlot: visualization of genomic data in chromosomal context
KY Oróstica, RA Verdugo - Bioinformatics, 2016 - academic.oup.com
Visualizing genomic data in chromosomal context can help detecting errors in data processing
and may suggest new hypotheses to be tested. Here, we report a new tool for displaying …
and may suggest new hypotheses to be tested. Here, we report a new tool for displaying …
Mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants
The emergence of SARS-CoV-2 variants of concern endangers the long-term control of
COVID-19, especially in countries with limited genomic surveillance. In this work, we explored …
COVID-19, especially in countries with limited genomic surveillance. In this work, we explored …
[HTML][HTML] Total mutational load and clinical features as predictors of the metastatic status in lung adenocarcinoma and squamous cell carcinoma patients
KY Oróstica, J Saez-Hidalgo, PR de Santiago… - Journal of Translational …, 2022 - Springer
Background Recently, extensive cancer genomic studies have revealed mutational and clinical
data of large cohorts of cancer patients. For example, the Pan-Lung Cancer 2016 dataset …
data of large cohorts of cancer patients. For example, the Pan-Lung Cancer 2016 dataset …
New year, new SARS-CoV-2 variant: Resolutions on genomic surveillance protocols to face Omicron
The emergence of SARS-CoV-2 variants with enhanced transmissibility and partial immune
escape (also known as Variants of Concern, VOC) has characterised the second year of the …
escape (also known as Variants of Concern, VOC) has characterised the second year of the …
Longitudinal study of wound healing status and bacterial colonisation of Staphylococcus aureus and Corynebacterium diphtheriae in epidermolysis bullosa patients
…, P Morandé, C Varela, K Oróstica… - International Wound …, 2023 - Wiley Online Library
Epidermolysis bullosa (EB) is an inherited disorder characterised by skin fragility and the
appearance of blisters and wounds. Patient wounds are often colonised or infected with …
appearance of blisters and wounds. Patient wounds are often colonised or infected with …
Model-based assessment of sampling protocols for infectious disease genomic surveillance
S Contreras, KY Oróstica, A Daza-Sanchez… - Chaos, Solitons & …, 2023 - Elsevier
Genomic surveillance of infectious diseases allows monitoring circulating and emerging
variants and quantifying their epidemic potential. However, due to the high costs associated …
variants and quantifying their epidemic potential. However, due to the high costs associated …
[HTML][HTML] A Comprehensive Analysis of the Effect of A> I (G) RNA-Editing Sites on Genotoxic Drug Response and Progression in Breast Cancer
Dysregulated A>I(G) RNA editing, which is mainly catalyzed by ADAR1 and is a type of post-transcriptional
modification, has been linked to cancer. A low response to therapy in breast …
modification, has been linked to cancer. A low response to therapy in breast …
Mining the relationship betweencar theft and places of social interest in santiago chile
K Oróstica, B Poblete - Companion proceedings of the 2019 world wide …, 2019 - dl.acm.org
Recent work suggests that certain places can be more attractive for car theft based how many
people regularly visit them, as well as other factors. In this sense, we must also consider …
people regularly visit them, as well as other factors. In this sense, we must also consider …
Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in Drosophila melanogaster
GH Olivares, F Núñez-Villegas, N Candia, K Oróstica… - Sleep, 2023 - academic.oup.com
The mechanisms by which the genotype interacts with nutrition during development to
contribute to the variation of complex behaviors and brain morphology of adults are not well …
contribute to the variation of complex behaviors and brain morphology of adults are not well …
BEST: a Shiny/R web-based application to easily retrieve cross-related enzyme functional parameters and information from BRENDA
JS Hidalgo, KY Oróstica, A Sanchez–Daza… - …, 2021 - academic.oup.com
Motivation BRENDA is the largest enzyme functional database, containing information of 84
000 experimentally characterized enzyme entries. This database is an invaluable resource …
000 experimentally characterized enzyme entries. This database is an invaluable resource …