Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
…, D Tabechian, LB Hughes, K Salomon-Escoto… - Nature …, 2019 - nature.com
To define the cell populations that drive joint inflammation in rheumatoid arthritis (RA), we
applied single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk RNA sequencing (…
applied single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk RNA sequencing (…
Inequity in access to bDMARD care and how it influences disease outcomes across countries worldwide: results from the METEOR-registry
…, D Vega-Morales, K Salomon-Escoto… - Annals of the …, 2018 - ard.bmj.com
Objective To establish in a global setting the relationships between countries’
socioeconomic status (SES), measured biological disease modifying antirheumatic drug (bDMARD)-…
socioeconomic status (SES), measured biological disease modifying antirheumatic drug (bDMARD)-…
The “treat to target” approach to rheumatoid arthritis
K Salomon-Escoto, J Kay - Rheumatic Disease Clinics, 2019 - rheumatic.theclinics.com
Rheumatoid arthritis (RA) is a systemic inflammatory disease that affects approximately 1%
of the population worldwide. If undertreated, patients are at risk for joint destruction and …
of the population worldwide. If undertreated, patients are at risk for joint destruction and …
Gastrointestinal and hepatic disease in Sjogren syndrome
Y Popov, K Salomon-Escoto - Rheumatic Disease Clinics, 2018 - rheumatic.theclinics.com
Sjogren syndrome (SS) is a lymphocyte-mediated, infiltrative autoimmune disorder
characterized by destruction of exocrine glands. The glandular damage leads to secretory …
characterized by destruction of exocrine glands. The glandular damage leads to secretory …
Assessment of control of rheumatoid arthritis disease activity
KI Salomon-Escoto, EM Gravallese, J Kay - Best Practice & Research …, 2011 - Elsevier
As very effective targeted biological therapies have become available to treat rheumatoid
arthritis (RA), remission is now the goal of treatment. Since 1981, efforts have been undertaken …
arthritis (RA), remission is now the goal of treatment. Since 1981, efforts have been undertaken …
How to treat patients with rheumatoid arthritis when methotrexate has failed? The use of a multiple propensity score to adjust for confounding by indication in …
…, E Murphy, A Chopra, K Salomon-Escoto… - Annals of the …, 2019 - ard.bmj.com
Objectives To compare consecutive disease modifying antirheumatic drug (DMARD)-treatment
regimes in daily practice in patients with rheumatoid arthritis (RA) who failed on initial …
regimes in daily practice in patients with rheumatoid arthritis (RA) who failed on initial …
The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation
…, AH Rupawala, K Salomon-Escoto… - … : Targets and Therapy, 2018 - Taylor & Francis
Background Tumor necrosis factor alpha (TNFα) is a key cytokine in both the pathogenesis
of inflammatory bowel disease (IBD) and rheumatoid arthritis (RA) and the host defense …
of inflammatory bowel disease (IBD) and rheumatoid arthritis (RA) and the host defense …
Autoantibody status is not associated with early treatment response to first-line methotrexate in patients with early rheumatoid arthritis
…, M Tikly, JE Fonseca, K Salomon-Escoto… - …, 2019 - academic.oup.com
Objectives In RA, the relationship between autoantibody status and treatment response to
MTX remains unclear. We investigated the association between autoantibody status and early …
MTX remains unclear. We investigated the association between autoantibody status and early …
Impact of the combined presence of erosions and ACPA on rheumatoid arthritis disease activity over time: results from the METEOR registry
SA Bergstra, MC Couto, N Govind, A Chopra… - RMD open, 2019 - rmdopen.bmj.com
Objective To investigate associations between baseline presence of erosions and/or anti-citrullinated
protein antibodies (ACPA) on functional ability, disease activity and treatment …
protein antibodies (ACPA) on functional ability, disease activity and treatment …
Association of 17 definitions of remission with functional status in a large clinical practice cohort of patients with rheumatoid arthritis
…, D Vega-Morales, K Salomon-Escoto… - The Journal of …, 2020 - jrheum.org
Objective. To compare the association between different remission criteria and physical
function in patients with rheumatoid arthritis followed in clinical practice. Methods. Longitudinal …
function in patients with rheumatoid arthritis followed in clinical practice. Methods. Longitudinal …