Cadmium stress: an oxidative challenge
At the cellular level, cadmium (Cd) induces both damaging and repair processes in which
the cellular redox status plays a crucial role. Being not redox-active, Cd is unable to generate …
the cellular redox status plays a crucial role. Being not redox-active, Cd is unable to generate …
Measuring DNA modifications with the comet assay: a compendium of protocols
…, S Shaposhnikov, V Sipinen, K Smeets… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic
cells, from yeast to human. The types of damage detected encompass DNA strand breaks …
cells, from yeast to human. The types of damage detected encompass DNA strand breaks …
Cadmium exposure in the population: from health risks to strategies of prevention
We focus on the recent evidence that elucidates our understanding about the effects of
cadmium (Cd) on human health and their prevention. Recently, there has been substantial …
cadmium (Cd) on human health and their prevention. Recently, there has been substantial …
The cellular redox state as a modulator in cadmium and copper responses in Arabidopsis thaliana seedlings
A Cuypers, S Karen, R Jos, O Kelly, K Els… - Journal of plant …, 2011 - Elsevier
The cellular redox state is an important determinant of metal phytotoxicity. In this study we
investigated the influence of cadmium (Cd) and copper (Cu) stress on the cellular redox …
investigated the influence of cadmium (Cd) and copper (Cu) stress on the cellular redox …
Induction of oxidative stress and antioxidative mechanisms in Phaseolus vulgaris after Cd application
K Smeets, A Cuypers, A Lambrechts, B Semane… - Plant Physiology and …, 2005 - Elsevier
Oxidative stress has been shown to be of great importance in the toxicity of several metals (copper,
zinc, …). In this study, the relationship of cadmium phytotoxicity and antioxidative …
zinc, …). In this study, the relationship of cadmium phytotoxicity and antioxidative …
Normalisation of real-time RT-PCR gene expression measurements in Arabidopsis thaliana exposed to increased metal concentrations
T Remans, K Smeets, K Opdenakker, D Mathijsen… - Planta, 2008 - Springer
Accurate quantification by real-time RT-PCR relies on normalisation of the measured gene
expression data. Normalisation with multiple reference genes is becoming the standard, but …
expression data. Normalisation with multiple reference genes is becoming the standard, but …
[HTML][HTML] Cadmium-induced pathologies: where is the oxidative balance lost (or not)?
AR Nair, O DeGheselle, K Smeets… - International journal of …, 2013 - mdpi.com
Over the years, anthropogenic factors have led to cadmium (Cd) accumulation in the environment
causing various health problems in humans. Although Cd is not a Fenton-like metal, it …
causing various health problems in humans. Although Cd is not a Fenton-like metal, it …
The need for transparency and good practices in the qPCR literature
…, K Schmidt-Bleek, K Skovgaard, K Smeets… - Nature …, 2013 - nature.com
Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR)
reveal a lack of transparent and comprehensive reporting of essential technical …
reveal a lack of transparent and comprehensive reporting of essential technical …
Cadmium responses in Arabidopsis thaliana: glutathione metabolism and antioxidative defence system
B Semane, A Cuypers, K Smeets… - Physiologia …, 2007 - Wiley Online Library
We investigated the effect of cadmium (Cd) on leaves of 3‐week‐old Arabidopsis thaliana
with a particular interest on glutathione (GSH) production and consumption, and antioxidative …
with a particular interest on glutathione (GSH) production and consumption, and antioxidative …
Cadmium-induced transcriptional and enzymatic alterations related to oxidative stress
K Smeets, J Ruytinx, B Semane… - Environmental and …, 2008 - Elsevier
The early antioxidative defence mechanisms were studied in Arabidopsis thaliana by applying
a range of realistic Cd concentrations. Our data suggest that a 24h exposure to 20μM …
a range of realistic Cd concentrations. Our data suggest that a 24h exposure to 20μM …