Cadmium stress: an oxidative challenge

…, TJ Artois, T Nawrot, J Vangronsveld, K Smeets - Biometals, 2010 - Springer
At the cellular level, cadmium (Cd) induces both damaging and repair processes in which
the cellular redox status plays a crucial role. Being not redox-active, Cd is unable to generate …

Measuring DNA modifications with the comet assay: a compendium of protocols

…, S Shaposhnikov, V Sipinen, K Smeets… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic
cells, from yeast to human. The types of damage detected encompass DNA strand breaks …

Cadmium exposure in the population: from health risks to strategies of prevention

…, E Munters, A Cuypers, T Richart, A Ruttens, K Smeets… - Biometals, 2010 - Springer
We focus on the recent evidence that elucidates our understanding about the effects of
cadmium (Cd) on human health and their prevention. Recently, there has been substantial …

The cellular redox state as a modulator in cadmium and copper responses in Arabidopsis thaliana seedlings

A Cuypers, S Karen, R Jos, O Kelly, K Els… - Journal of plant …, 2011 - Elsevier
The cellular redox state is an important determinant of metal phytotoxicity. In this study we
investigated the influence of cadmium (Cd) and copper (Cu) stress on the cellular redox …

Induction of oxidative stress and antioxidative mechanisms in Phaseolus vulgaris after Cd application

K Smeets, A Cuypers, A Lambrechts, B Semane… - Plant Physiology and …, 2005 - Elsevier
Oxidative stress has been shown to be of great importance in the toxicity of several metals (copper,
zinc, …). In this study, the relationship of cadmium phytotoxicity and antioxidative …

Normalisation of real-time RT-PCR gene expression measurements in Arabidopsis thaliana exposed to increased metal concentrations

T Remans, K Smeets, K Opdenakker, D Mathijsen… - Planta, 2008 - Springer
Accurate quantification by real-time RT-PCR relies on normalisation of the measured gene
expression data. Normalisation with multiple reference genes is becoming the standard, but …

[HTML][HTML] Cadmium-induced pathologies: where is the oxidative balance lost (or not)?

AR Nair, O DeGheselle, K Smeets… - International journal of …, 2013 - mdpi.com
Over the years, anthropogenic factors have led to cadmium (Cd) accumulation in the environment
causing various health problems in humans. Although Cd is not a Fenton-like metal, it …

The need for transparency and good practices in the qPCR literature

…, K Schmidt-Bleek, K Skovgaard, K Smeets… - Nature …, 2013 - nature.com
Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR)
reveal a lack of transparent and comprehensive reporting of essential technical …

Cadmium responses in Arabidopsis thaliana: glutathione metabolism and antioxidative defence system

B Semane, A Cuypers, K Smeets… - Physiologia …, 2007 - Wiley Online Library
We investigated the effect of cadmium (Cd) on leaves of 3‐week‐old Arabidopsis thaliana
with a particular interest on glutathione (GSH) production and consumption, and antioxidative …

Cadmium-induced transcriptional and enzymatic alterations related to oxidative stress

K Smeets, J Ruytinx, B Semane… - Environmental and …, 2008 - Elsevier
The early antioxidative defence mechanisms were studied in Arabidopsis thaliana by applying
a range of realistic Cd concentrations. Our data suggest that a 24h exposure to 20μM …