User profiles for Kari Nadeau

Kari Nadeau

Harvard
Verified email at hsph.harvard.edu
Cited by 48170

[HTML][HTML] Personal omics profiling reveals dynamic molecular and medical phenotypes

…, AJ Butte, EA Ashley, M Gerstein, KC Nadeau… - Cell, 2012 - cell.com
Personalized medicine is expected to benefit from combining genomic information with regular
monitoring of physiological states by multiple high-throughput methods. Here, we present …

Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19

…, MC Brüggen, L O'Mahony, Y Gao, K Nadeau… - Allergy, 2020 - Wiley Online Library
As a zoonotic disease that has already spread globally to several million human beings and
possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) …

Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome

…, S Gombar, R Tibshirani, KC Nadeau… - Science …, 2020 - science.org
SARS-CoV-2-specific antibodies, particularly those preventing viral spike receptor binding
domain (RBD) interaction with host angiotensin-converting enzyme 2 (ACE2) receptor, can …

Prevalence and severity of food allergies among US adults

…, MM Davis, RP Schleimer, KC Nadeau - JAMA network …, 2019 - jamanetwork.com
Importance Food allergy is a costly, potentially life-threatening condition. Although studies
have examined the prevalence of childhood food allergy, little is known about prevalence, …

[HTML][HTML] Systems vaccinology of the BNT162b2 mRNA vaccine in humans

…, MM Davis, PJ Utz, MS Suthar, P Khatri, KC Nadeau… - Nature, 2021 - nature.com
The emergency use authorization of two mRNA vaccines in less than a year from the emergence
of SARS-CoV-2 represents a landmark in vaccinology 1 , 2 . Yet, how mRNA vaccines …

Distribution of ACE2, CD147, CD26, and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension …

…, N Lunjani, C Traidl‐Hoffmann, KC Nadeau… - Allergy, 2020 - Wiley Online Library
Background Morbidity and mortality from COVID‐19 caused by novel coronavirus SARS‐CoV‐2
is accelerating worldwide, and novel clinical presentations of COVID‐19 are often …

Food allergy: a practice parameter update—2014

…, SA Bock, J James, S Jones, D Lang, K Nadeau… - Journal of Allergy and …, 2014 - Elsevier
This parameter was developed by the Joint Task Force on Practice Parameters, representing
the American Academy of Allergy, Asthma & Immunology (AAAAI); the American College of …

[HTML][HTML] New-onset IgG autoantibodies in hospitalized patients with COVID-19

…, JA James, PS Kim, NJ Meyer, KC Nadeau… - Nature …, 2021 - nature.com
COVID-19 is associated with a wide range of clinical manifestations, including autoimmune
features and autoantibody production. Here we develop three protein arrays to measure IgG …

The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand.

M Takada, KC Nadeau, GD Shaw… - The Journal of …, 1997 - Am Soc Clin Investig
The Cytokine-adhesion Molecule Cascade in Ischemia/Reperfusion Injury of the Rat Kidney
Page 1 2682 Takada et al. J. Clin. Invest. © The American Society for Clinical Investigation, Inc …

Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing

…, B Hanczaruk, KD Nguyen, KC Nadeau… - Science translational …, 2009 - science.org
The complex repertoire of immune receptors generated by B and T cells enables recognition
of diverse threats to the host organism. Here, we show that massively parallel DNA …