[PDF][PDF] A LIN28B-RAN-AURKA signaling network promotes neuroblastoma tumorigenesis

…, SE Chodosh, DA Oldridge, ME Gagliardi, KL Conkrite… - Cancer cell, 2015 - cell.com
A more complete understanding of aberrant oncogenic signaling in neuroblastoma, a
malignancy of the developing sympathetic nervous system, is paramount to improving patient …

Telomere maintenance mechanisms define clinical outcome in high-risk neuroblastoma

B Koneru, G Lopez, A Farooqi, KL Conkrite, TH Nguyen… - Cancer research, 2020 - AACR
These findings assess telomere maintenance mechanisms with TERT mRNA and the ALT
DNA biomarker C-circles to stratify neuroblastoma into three groups, with distinct overall …

[HTML][HTML] Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma

LD McDaniel, KL Conkrite, X Chang, M Capasso… - PLoS …, 2017 - journals.plos.org
Neuroblastoma is a cancer of the developing sympathetic nervous system that most commonly
presents in young children and accounts for approximately 12% of pediatric oncology …

[HTML][HTML] Epigenomic profiling of neuroblastoma cell lines

K Upton, A Modi, K Patel, NM Kendsersky, KL Conkrite… - Scientific data, 2020 - nature.com
Understanding the aberrant transcriptional landscape of neuroblastoma is necessary to
provide insight to the underlying influences of the initiation, progression and persistence of this …

Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa

…, FA Middleton, KL Conkrite… - Proceedings of the …, 2006 - National Acad Sciences
Fertility of spermatozoa depends on maintenance of the mitochondrial transmembrane
potential (Δψ m ), which is generated by the electron-transport chain and regulated by an …

Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival

…, R Kaufman, JP Evans, KL Conkrite… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Neuroblastoma is an embryonal cancer of the developing sympathetic nervous
system. The genetic contribution of rare pathogenic or likely pathogenic germline variants in …

Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma

G Lopez, KL Conkrite, M Doepner, KS Rathi… - Genome …, 2020 - genome.cshlp.org
Neuroblastoma is a malignancy of the developing sympathetic nervous system that accounts
for 12% of childhood cancer deaths. Like many childhood cancers, neuroblastoma shows a …

Integrative Genomic Analyses Identify LncRNA Regulatory Networks across Pediatric Leukemias and Solid Tumors

A Modi, G Lopez, KL Conkrite, C Su, TC Leung… - Cancer Research, 2023 - AACR
Comprehensive characterization of lncRNAs in pediatric cancer leads to the identification of
highly expressed lncRNAs across childhood cancers, annotation of lncRNAs showing …

[HTML][HTML] Germline pathogenic variants in 786 neuroblastoma patients

…, LE Egolf, R Kaufman, JP Evans, KL Conkrite… - medRxiv, 2023 - ncbi.nlm.nih.gov
… Mosse YP, Laudenslager M, Longo L, et al. Identification of ALK as a major familial
neuroblastoma predisposition gene. Nature. … Akhavanfard S, Padmanabhan R, Yehia L …

Efficient syntheses of four stable-isotope labeled (1 R)-menthyl (1 S, 2 S)-(+)-2-phenylcyclopropanecarboxylates

…, RC Burrell, HR Chobanian, KL Conkrite… - Organic & …, 2006 - pubs.rsc.org
Many carbenoid cyclopropanation reactions promoted by chiral catalysts give product
mixtures reflecting impressive diastereo- and enantioselectivities. Few provide a single chiral …