Myelin regeneration can occur in the brain following demyelination. Parenchymal oligodendrocyte
progenitors (pOPC) are known to play a crucial role in this process. Neural stem cells (…

It is widely thought that brain repair does not occur, but myelin regeneration provides clear
evidence to the contrary. Spontaneous remyelination may occur after injury or in multiple …

Objective: Multiple sclerosis is a neurodegenerative disease characterized by episodes of
immune attack of oligodendrocytes leading to demyelination and progressive functional deficit…

Since the discovery of adult neural stem cells, mobilization of endogenous stem cells from
the subventricular zone (SVZ) emerges as a promising strategy to promote brain repair. Here, …

Understanding the signals that control migration of neural progenitor cells in the adult brain
may provide new therapeutic opportunities. Reelin is best known for its role in regulating cell …

Ciliary neurotrophic factor (CNTF) has been shown to be expressed after brain lesions and
in particular after demyelination. Here, we addressed the role of this cytokine in the …

In the adult rodent brain, the subventricular zone (SVZ) represents a special niche for neural
stem cells; these cells proliferate and generate neural progenitors. Most of these migrate …

Myelin destruction is followed by resident glia activation and mobilization of endogenous
progenitors (OPC) which participate in myelin repair. Here we show that in response to …

In pituitary cells, transcriptional regulation of the prolactin (PRL) gene and prolactin secretion
are controlled by multiple transduction pathways through the activation of G protein …

Vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase-activating
polypeptide (PACAP38) regulate anterior pituitary cell secretion and proliferation. In the …