User profiles for Karishma Patel

Karishma V. Patel

RAND Corporation
Verified email at rand.org
Cited by 113

[HTML][HTML] A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection

…, ND Bhattacharyya, A Grey, O Hutchings, K Patel… - npj Vaccines, 2021 - nature.com
Global control of COVID-19 requires broadly accessible vaccines that are effective against
SARS-CoV-2 variants. In this report, we exploit the immunostimulatory properties of bacille …

A novel design of artificial membrane for improving the PAMPA model

X Chen, A Murawski, K Patel, CL Crespi… - Pharmaceutical …, 2008 - Springer
Purpose Since the first demonstration of PAMPA, the artificial membrane has been traditionally
prepared by impregnating a porous filter with a solution of lipid mixture. While the lipid …

[BOOK][B] Critical care surge response strategies for the 2020 COVID-19 outbreak in the United States

…, EWM Chan, H Al Ibrahim, C Cutter, K Patel… - 2020 - researchgate.net
The coronavirus disease 2019 (COVID-19) pandemic is placing extraordinary strains on the
US medical system, most especially hospitals. Hospitals are searching for ways to ramp up …

[HTML][HTML] Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs

…, F Chung, A Aggarwal, JKK Low, K Patel… - PLoS …, 2023 - journals.plos.org
Although ACE2 is the primary receptor for Severe Acute Respiratory Syndrome Coronavirus
2 (SARS-CoV-2) infection, a systematic assessment of host factors that regulate binding to …

The effect of collection substrate on electrospun ciprofloxacin-loaded poly (vinylpyrrolidone) and ethyl cellulose nanofibers as potential wound dressing materials

…, YJ Chiu, U Angkawinitwong, K Patel… - Materials Science and …, 2019 - Elsevier
In this work, nanofibers based on hydrophilic poly(vinylpyrrolidone) (PVP) and hydrophobic
ethyl cellulose (EC) were generated via electrospinning. A model antibiotic, ciprofloxacin (…

[HTML][HTML] Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine

…, S Huhmann, N Proschogo, K Patel… - Nature …, 2022 - nature.com
The importance of modified peptides and proteins for applications in drug discovery, and for
illuminating biological processes at the molecular level, is fueling a demand for efficient …

[HTML][HTML] A novel purification procedure for active recombinant human DPP4 and the inability of DPP4 to bind SARS-CoV-2

CR Xi, A Di Fazio, NA Nadvi, K Patel, MSW Xiang… - Molecules, 2020 - mdpi.com
Proteases catalyse irreversible posttranslational modifications that often alter a biological
function of the substrate. The protease dipeptidyl peptidase 4 (DPP4) is a pharmacological …

The incidence and severity of postoperative pain following inpatient surgery

A Buvanendran, J Fiala, KA Patel, AD Golden… - Pain …, 2015 - academic.oup.com
Objective In recent years, there has been increased attention to pain management after surgery
in the hospital setting along with financial enticement from the US government. The aim …

[HTML][HTML] CHD4 slides nucleosomes by decoupling entry-and exit-side DNA translocation

…, DP Ryan, JKK Low, C Franck, K Patel… - Nature …, 2020 - nature.com
Chromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers.
The mechanism, however, is only partially resolved, and it is unclear if it is conserved …

Effect of bariatric surgery-induced weight loss on renal and systemic inflammation and blood pressure: a 12-month prospective study

…, S Dubb, M Bueter, F Seyfried, K Patel… - Surgery for Obesity and …, 2013 - Elsevier
Background Bariatric surgery improves arterial hypertension and renal function; however,
the underlying mechanisms and effect of different surgical procedures are unknown. In the …